关键词: 脑出血; 肺部感染; 影响因素; 干预

Abstract:

Objective To investigate the influence factors of pulmonary infection (PI) in patients with spontaneous cerebral hemorrhage. Methods A retrospective analysis of clinical data of 228 patients with spontaneous cerebral hemorrhage in Huangshi Central Hospital from June 2015 to June 2018 were performed, to analyze the influence factors of PI in these patients. Results Of 228 patients with spontaneous cerebral hemorrhage, 100 cases (43.67%) had PI, and 148 pathogenic bacteria strains were isolated, including 128 strains (86.48%) of Gram-negative bacteria, 10 strains (6.76%) of Gram-positive bacteria and 10 strains (6.76%) of fungus. The single factor analysis results showed that age, smoking, dysphagia, GCS score, cerebral hemorrhage volume, airway invasive operation, nasal feeding, diabetes, lung diseases, hypoproteinemia were associated with PI after spontaneous cerebral hemorrhage (all P <0.05). The Logistic regression analysis showed that age ≥ 60 years,smoking,dysphagia, GCS score <8, bleeding volume ≥100 mL, airway invasive operation,nasal feeding, diabetes, lung disease, hypoproteinemia were independent risk factors of PI after spontaneous cerebral hemorrhage (P <0.05). Conclusions The incidence of PI after spontaneous cerebral hemorrhage is high, the strains of PI is mainly Gram-negative bacteria. PI occurrence is related with a variety of factors, especially age ≥60 years, smoking, dysphagia, GCS score <8, bleeding volume ≥100 mL, airway invasive operation, nasal feeding, diabetes, lung disease and hypoproteinemia. The patients with the above factors should be given more attention and timely intervention.

Key words: Cerebral hemorrhage; Pulmonary infection; Influence factor; Intervention