Objective To explore the effect of computer simulated training on cognition in patients with
vascular cognitive impairment (VCI), so as to provide effective treatment for patients with VCI.
Methods A total of 80 patients diagnosed with VCI in Department of Neurology of the hospital
during October 2015 to November 2016 were enrolled in this study. The patients were randomized
into control (n =30) and intervention (n =50) group at a ratio of 3 : 5. All patients were evaluated by
the Montreal Cognitive Assessment (MoCA) and computer cognitive evaluation visual attention,
reasoning, spatial imagination, calculation, speech memory, reading, word recognition, immediaterecall
of pictures and execution ability under the guide of experienced neurologists. The control
group only received conventional drug therapy. On the basis of conventional drug therapy, theintervention group received computer simulated training for a period of 30 to 60 days by trained
neurologists, 1 h per time. Both groups received multidimensional recognition evaluation after 30
times of exercise. The intervention effect including visual attention, reasoning, spatial imagination,
calculation, speech memory, reading, word recognition, immediate-recall of pictures and execution
ability were observed.
Results Analysis the basic data found that gender, age, education level of the two groups of patients
were of no significant difference. The control and intervention groups did not differ on baseline
cognition abilities. In MoCA scale, despite of the direction ability had no obvious change, the other
cognitive sub-items were improved after computer simulated training in treatment group (P <0.05)
and 9 sub-items all got improved (P <0.05). In addition to the reasoning (P =0.06) and speech memory
abilities (P =0.01) decreased of the control group, the other cognitive sub-items had no obvious
change. Compared with control group, computer simulated training led improvement in visual
attention, reasoning, spatial imagination, calculation, speech memory, reading, word recognition, and
immediate-recall of pictures and execution ability (P <0.05).
Conclusion Computer-based cognitive function training can improve vascular cognitive
impairment in different degrees, including visual attention, reasoning, spatial imagination,
calculation, speech memory, reading, word recognition, immediate-recall of pictures and execution
ability, which provides a new mean of intervention for VCI.
