Research Progress on Predicting Futile Recanalization following Endovascular Treatment in Acute Ischemic Stroke

doi:10.3969/j.issn.1673-5765.2026.03.013

Abstract

Abstract: Endovascular treatment stands as the primary reperfusion therapy for patients with large vessel occlusion ischemic stroke. However, an increasing number of studies have shown that even with successful recanalization of the occluded vessels, a significant proportion of patients still experience poor functional outcomes, which is known as futile recanalization. Early predictive assessment of the risk of futile recanalization is crucial for developing individualized treatment strategies and improving clinical prognosis. This review comprehensively synthesizes the predictive assessment studies of futile recanalization following endovascular treatment in acute ischemic stroke, aiming to provide novel insights that enable clinicians to identify patients at high risk of futile recanalization early and thus make evidence-based clinical treatment decisions.

Key words: Acute ischemic stroke; Futile recanalization; Endovascular treatment

摘要： 血管内治疗是大血管闭塞性缺血性卒中患者再灌注治疗的主要方法，然而，越来越多的研究表明，即使成功开通闭塞血管，仍有部分患者存在不良功能预后，即无效再通。早期预测无效再通的发生风险，是制订个体化治疗方案、改善患者临床预后的重要环节。本综述对急性缺血性卒中血管内治疗后无效再通的预测研究进行综合梳理，以期为临床医师早期识别无效再通高风险患者、制订合理的临床治疗决策提供新思路。

关键词: 急性缺血性卒中; 无效再通; 血管内治疗

CLC Number:

ZHANG Zili, ZHAO Ying, MENG Heng, XU Anding. Research Progress on Predicting Futile Recanalization following Endovascular Treatment in Acute Ischemic Stroke[J]. Chinese Journal of Stroke, 2026, 21(3): 378-386.

张自立, 赵颖, 孟珩, 徐安定. 急性缺血性卒中血管内治疗后无效再通预测研究进展[J]. 中国卒中杂志, 2026, 21(3): 378-386.

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URL: https://www.chinastroke.org.cn/EN/10.3969/j.issn.1673-5765.2026.03.013

https://www.chinastroke.org.cn/EN/Y2026/V21/I3/378

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