代谢性脑血管病的“多系统对话”与“多学科共管”

doi:10.3969/j.issn.1673-5765.2024.02.001

中国卒中杂志 ›› 2024, Vol. 19 ›› Issue (2): 125-129.DOI: 10.3969/j.issn.1673-5765.2024.02.001

代谢性脑血管病的“多系统对话”与“多学科共管”

许杰, 王拥军

北京 100070 首都医科大学附属北京天坛医院神经病学中心，国家神经系统疾病临床医学研究中心

收稿日期:2024-01-04 出版日期:2024-02-20 发布日期:2024-02-20
通讯作者: 王拥军 yongjunwang@ncrcnd.org.cn
基金资助:
国家重点研发计划（2022YFC2502400；2022YFC2502403）

“Multi-System Dialogue” and “Multi-Disciplinary Co-Management” of Cerebro-Metabolic Disease

XU Jie, WANG Yongjun

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China; China National Clinical Research Center for Neurological Diseases, Beijing 100070, China

Received:2024-01-04 Online:2024-02-20 Published:2024-02-20
Contact: WANG Yongjun, E-mail: yongjunwang@ncrcnd.org.cn

摘要/Abstract

摘要： 代谢性脑血管病是一个新近提出的概念，指由传统代谢危险因素和残余代谢危险因素引起的脑血管损害，通过干预代谢危险因素可有效改善其预后的一种临床综合征。代谢途径并非独立存在，脑、心脏、肝脏、肾脏和肠道等多个器官的各种代谢途径相互影响、共同作用、交织成网，构成了人体的代谢网络，而代谢网络的异常导致了代谢性脑血管病的发生。同时，代谢危险因素的存在可同时造成多个靶器官损害，且神经系统与心血管系统、内分泌系统、消化系统等可通过多种病理生理过程相互影响。因此，代谢性脑血管病未来在机制探究和疾病治疗等方面将逐渐倾向于多器官水平，并向多学科管理模式发展。

关键词: 代谢性脑血管病; 脑血管代谢风险; 多学科综合管理

Abstract: Cerebro-metabolic disease is a recently proposed concept primarily referring to cerebrovascular injury caused by both traditional and residual metabolic risk factors. It represents a clinical syndrome in which intervention in metabolic risk factors can effectively improve the prognosis. Metabolic pathways do not exist independently. Various metabolic pathways in multiple organs such as the brain, heart, liver, kidneys, and intestines interact, collaborate, and intertwine to form the metabolic network of the human body. The abnormality in the metabolic network leads to the occurrence of cerebro-metabolic disease. Moreover, the presence of metabolic risk factors can simultaneously cause injury to multiple target organs, and the nervous system interacts with the cardiovascular system, endocrine system, digestive system, and others through various pathophysiological processes. Therefore, future research on cerebro-metabolic disease will gradually tend to multi-organ level in mechanism exploration and disease treatment, and develop into a multidisciplinary management approach.

Key words: Cerebro-metabolic disease; Cerebro-metabolic risk; Comprehensive multidisciplinary management

中图分类号:

许杰, 王拥军. 代谢性脑血管病的“多系统对话”与“多学科共管”[J]. 中国卒中杂志, 2024, 19(2): 125-129.

XU Jie, WANG Yongjun. “Multi-System Dialogue” and “Multi-Disciplinary Co-Management” of Cerebro-Metabolic Disease[J]. Chinese Journal of Stroke, 2024, 19(2): 125-129.

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代谢性脑血管病的“多系统对话”与“多学科共管”

“Multi-System Dialogue” and “Multi-Disciplinary Co-Management” of Cerebro-Metabolic Disease

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