关键词: 高血压脑出血; 脑血管造影术; 血肿

Abstract: Objective To explore the spot sign on computed tomography angiography source image(CTA-SI) in order to assist in individualizing therapeutic decisions for patients by possibly forecasting hematoma enlargement.Methods Fifty-three patients with spontaneous intracerebral hemorrhage(ICH) were examined by non-contrast computed tomography(CT) and computed tomography angiography(CTA) within 6 hours after symptom onset. CTA-SI was reviewed by 3 neuroradiologists to make sure presence or absence of the spot sign. Hematoma volumes were determined from non-contrast CT images and compared between first and second CT images.Results Thirteen patients(24.5%) present of spot sign. Hematoma expansion occurred in 15 patients(28.3%) on follow-up. In which 12 patients present of spot sign. Sensitivity, specificity, positive predictive value, and negative predictive value for expansion were 80.0%, 97.4%, 92.3%, 92.5%, respectively. In patients with the spot sign, hematoma volume has significant difference in first and second CT images(P<0.05). In patients without the spot sign, hematoma volume has no significant difference in first and second CT images(P>0.05).Conclusions In acute ICH patients, CTA spot sign provided more radiological information that maybe assisted in individualizing therapeutic decisions for patients by possibly forecasting hematoma enlargement.

Key words: Intracranial hemorrhage; hypertensive; Cerebral angiography; Hematoma