Atrial Fibrillation and Dementia

doi:10.3969/j.issn.1673-5765.2017.02.019

Abstract

Abstract:

Study found that atrial fibrillation was an independent risk factor for dementia. Atrial fibrillation can lead to atrial thrombus formation and high risk of concurrent systemic embolism after falling off emboli. When the embolus blocked small blood vessels in the brain, damage of sufficient capacity of the brain tissue can cause vascular dementia. Therefore, if the pathogenesis mechanism and risk factors of the two could be understood, we could block this mechanism by treatment and reduce risk factors so as to reduce dementia caused by atrial fibrillation. However, under or over anticoagulation can lead to dementia.

Key words: Atrial fibrillation; Dementia; Alzheimer’s disease; Review

摘要：

研究发现，心房颤动（简称房颤）是痴呆相关的高危独立因素。心房颤动易引起心房产生血栓，栓子脱落后，并发体循环栓塞的风险极大。当栓子堵住脑部小血管时，损害足够容量的脑组织，就会引起血管性痴呆。因此，如果可以研究清楚二者之间的发病机制和危险因素，通过治疗阻断这一机制，并减少二者发生的危险因素，就会减少由心房颤动引发的痴呆。然而，抗凝不足或过度抗凝都会导致痴呆。

关键词: 心房颤动; 痴呆; 阿尔茨海默症; 综述

WU Chong-Guang, CHAI Qin-Qin, SONG Yan-Li, et al.. Atrial Fibrillation and Dementia[J]. Chinese Journal of Stroke, 2017, 12(02): 188-191.

武崇光，柴琴琴，宋彦丽，林杰，武一平. 心房颤动与痴呆[J]. 中国卒中杂志, 2017, 12(02): 188-191.

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