[1] ETMINAN M,TAKKOUCHE B,ISORNA F C,etal. Risk of ischaemic stroke in people with migraine:systematic review and meta-analysis of observationalstudies[J]. BMJ,2005,330(7482):63.[2] ABANOZ Y,GULEN ABANOZ Y,GUNDUZ A,et al. Migraine as a risk factor for young patientswith ischemic stroke:a case-control study[J].Neurological sciences,2017,38(4):611-617.[3] Headache Classification Committee of theInternational Headache Society(IHS). TheInternational Classification of Headache Disorders,3rd edition(beta version)[J]. Cephalalgia,2013,33(9):629-808.[4] WOLF M E,SZABO K,GRIEBE M,et al. Clinicaland MRI characteristics of acute migrainousinfarction[J]. Neurology,2011,76(22):1911-1917.[5] LAURELL K,ARTTO V,BENDTSEN L,et al.Migrainous infarction:a Nordic multicenter study[J].Eur J Neurol,2011,18(10):1220-1226.[6] DALKARA T,NOZARI A,MOSKOWITZ M A.Migraine aura pathophysiology:the role of bloodvessels and microembolisation[J]. Lancet Neurol,2010,9(3):309-317.[7] WOLF M E,JAGER T,BAZNER H,et al. Changesin functional vasomotor reactivity in migraine withaura[J]. Cephalalgia,2009,29(11):1156-1164.[8] WANG S B,LIU K D,YANG Y,et al. Prevalenceand extent of right-to-left shunt on contrastenhancedtranscranial Doppler in Chinese patientswith migraine in a multicentre case-control study[J/OL]. Cephalalgia,2017,333102417708203. https://doi.org/10.1177/0333102417708203.[9] SCHWEDT T J,DEMAERSCHALK B M,DODICK D W. Patent foramen ovale and migraine:aquantitative systematic review[J]. Cephalalgia,2008,28(5):531-540.[10] 武春桃,白晶,郭珍妮,等. 195例正常人右向左分流发生率及特点的研究[J]. 中国卒中杂志,2014,9(3):193-196.[11] ANDROULAKIS X M,KODUMURI N,GIAMBERARDINO L D,et al. Ischemic strokesubtypes and migraine with visual aura in the ARICstudy[J]. Neurology,2016,87(24):2527-2532.[12] GUO Z N,XING Y,LIU J,et al. Compromiseddynamic cerebral autoregulation in patients witha right-to-left shunt:a potential mechanism ofmigraine and cryptogenic stroke[J/OL]. PloS one,2014,9(8):e104849. https://doi.org/10.1371/journal.pone.0104849.[13] METSO T M,TATLISUMAK T,DEBETTE S,et al.Migraine in cervical artery dissection and ischemicstroke patients[J]. Neurology,2012,78(16):1221-1228.[14] DE GIULI V,GRASSI M,LODIGIANI C,et al.Association Between Migraine and Cervical ArteryDissection:The Italian Project on Stroke in YoungAdults[J]. JAMA Neurol,2017,74(5):512-518.[15] DEBETTE S,KAMATANI Y,METSO T M,et al.Common variation in PHACTR1 is associated withsusceptibility to cervical artery dissection[J]. NatGenet,2015,47(1):78-83.[16] TZOURIO C,TEHINDRAZANARIVELO A,IGLESIAS S,et al. Case-control study of migraineand risk of ischaemic stroke in young women[J].BMJ,1995,310(6983):830-833.[17] CURTIS K M,MOHLLAJEE A P,PETERSON H B.Use of combined oral contraceptives among womenwith migraine and nonmigrainous headaches:asystematic review[J]. Contraception,2006,73(2):189-194.[18] CALHOUN A,FORD S,PRUITT A. The impactof extended-cycle vaginal ring contraceptionon migraine aura:a retrospective case series[J]. Headache,2012,2(8):1246-1253.[19] CHANG C L,DONAGHY M,POULTER N.Migraine and stroke in young women:case-controlstudy. The World Health Organisation CollaborativeStudy of Cardiovascular Disease and SteroidHormone Contraception[J]. BMJ,1999,318(7175):13-18.[20] SULAK P,WILLIS S,KUEHL T,et al. Headachesand oral contraceptives:impact of eliminating thestandard 7-day placebo interval[J]. Headache,2007,47(1):27-37.[21] TIMM F P,HOULE T T,GRABITZ S D,et al.Migraine and risk of perioperative ischemic strokeand hospital readmission:hospital based registrystudy[J/OL]. BMJ,2017,356:i6635. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225233/.doi:10.1136/bmj.i6635.[22] THORLUND K,SUN-EDELSTEIN C,DRUYTSE,et al. Risk of medication overuse headacheacross classes of treatments for acute migraine[J]. JHeadache Pain,2016,17(1):107.[23] ROBERTO G,RASCHI E,PICCINNI C,et al.Adverse cardiovascular events associated withtriptans and ergotamines for treatment of migraine:systematic review of observational studies[J].Cephalalgia,2015,35(2):118-131.[24] MARTIN V T,GOLDSTEIN J A. Evaluating thesafety and tolerability profile of acute treatmentsfor migraine[J]. Am J Med,2005,118(Suppl 1):36S-44S.[25] XING Y Q,GUO Y Z,GAO Y S,et al.Effectiveness and Safety of Transcatheter PatentForamen Ovale Closure for Migraine(EASTFORM)Trial[J/OL]. Sci Rep,2016,6:39081. https://doi.org/10.1038/srep39081.[26] DOWSON A,MULLEN M J,PEATFIELDR,et al. Migraine Intervention With STARFlexTechnology(MIST)trial:a prospective,multicenter,double-blind,sham-controlled trial to evaluate theeffectiveness of patent foramen ovale closure withSTARFlex septal repair implant to resolve refractorymigraine headache[J]. Circulation,2008,117(11):1397-1404.[27] MATTLE H P,EVERS S,HILDICK-SMITH D,etal. Percutaneous closure of patent foramen ovale inmigraine with aura,a randomized controlled trial[J].Eur Heart J,2016,37(26):2029-2036.[28] TOBIS J,CHARLES A,SILBERSTEIN S D,etal. TCT-30 PREMIUM Trial:Double blind study ofpercutaneous closure of patent foramen ovale withthe AMPLATZER® PFO Occluder as a treatmentfor migraine with or without aura[J/OL]. J Am CollCardio,2015,66(15,Supplement):B13. https://doi.org/10.1016/j.jacc.2015.08.076.[29] SONDERGAARD L,KASNER S E,RHODES J F,et al. Patent Foramen Ovale Closure or AntiplateletTherapy for Cryptogenic Stroke[J]. N Engl J Med,2017,377(11):1033-1042.[30] MAS J L,DERUMEAUX G,GUILLON B,et al.Patent Foramen Ovale Closure or Anticoagulation vs.Antiplatelets after Stroke[J]. N Engl J Med,2017,377(11):1011-1021.[31] SAVER J L,CARROLL J D,THALER D E,etal. Long-Term Outcomes of Patent Foramen OvaleClosure or Medical Therapy after Stroke[J]. N Engl JMed,2017,377(11):1022-1032.