Risk Factors and Outcomes of Pneumonia in Patients with Subarachnoid Hemorrhage

doi:10.3969/j.issn.1673-5765.2020.06.010

Abstract

Abstract:

Objective To analyze the influencing factors and in-hospital outcomes of pneumonia in patients with subarachnoid hemorrhage (SAH). Methods The data of SAH patients from Beijing Tian Tan Hospital, Capital Medical University from May, 2015 to November, 2018 were retrospectively analyzed. Based on the presence of inhospital pneumonia or not, all the patients were divided into pneumonia group and non-pneumonia group. The differences of clinical characteristics between the two groups were compared. The univariate and multivariate logistic regression were used to analyze the risk factors for pneumonia and the in-hospital outcome of patients with pneumonia. Results A total of 457 patients were included, with an average age of 54.3±11.2 years and 219 males (47.9%). Pneumonia occurred in 76 cases (16.6%). Multivariate analysis showed that male (OR 2.31, 95%CI 1.17-4.58, P =0.016), dysphagia (OR 6.06, 95%CI 1.09-33.70, P =0.039) and Barthel index of 0-20 points (OR 15.58, 95%CI 4.17-58.23, P <0.001) were independent risk factors for pneumonia, and pneumonia was not associated with in-hospital mortality, the length of hospitalization and the total expense of hospitalization. Conclusions Male, dysphagia and Barthel index of 0-20 points were independent risk factors for pneumonia in SAH patients. The occurrence of pneumonia did not increase the risk of in-hospital death, the length of hospitalization and the total expense of hospitalization.

Key words: Subarachnoid hemorrhage; Pneumonia; Risk Factor; Outcome

摘要：

目的分析蛛网膜下腔出血（subarachnoid hemorrhage，SAH）相关性肺炎发生的危险因素及其对住院结局的影响。方法回顾性纳入2015年5月-2018年11月首都医科大学附属北京天坛医院收治的SAH患者，根据住院期间是否发生肺炎分为肺炎组、非肺炎组，比较两组患者临床资料的差异。采用多因素Logistic回归模型，分析发生肺炎的危险因素，以及发生肺炎对SAH患者院内死亡、住院天数、住院总费用的影响。结果共纳入457例SAH患者，平均年龄54.3±11.2岁，男性219例（47.9%），发生肺炎76例（16.6%）。男性（OR 2.31,95%CI 1.17～4.58，P =0.016）、吞咽障碍（OR 6.06,95%CI 1.09～33.70，P =0.039）及 Barthel指数0～20分（OR 15.58,95%CI 4.17～58.23，P＜0.001）是SAH患者发生肺炎的独立危险因素；发生肺炎与院内死亡风险、住院天数和住院总费用增加无关。结论男性、吞咽障碍、Barthel指数0～20分是SAH患者发生肺炎的独立危险因素。发生肺炎与院内死亡风险、住院天数和住院总费用增加无关。

关键词: 蛛网膜下腔出血; 肺炎; 危险因素; 预后

邓永梅，李子孝，苗亚杰，赵性泉. 蛛网膜下腔出血相关性肺炎发生的危险因素分析及对住院结局的影响[J]. 中国卒中杂志, 2020, 15(06): 626-630.

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