XU Weihai, LI Shun, CHENG Anqi. Diagnosis and Treatment of Stroke in Young Adults: No Overtreatment[J]. Chinese Journal of Stroke, 2022, 17(09): 915-918.
[1]BÉJOT Y，DULOQUIN G，THOMAS Q，et al. Temporal trends in the incidence of ischemic stroke in young adults：Dijon stroke registry[J]. Neuroepidemiology，2021，55（3）：239-244.
[2]NIU J W，GAO S，CUI L Y，et al. Intracranial atherosclerosis in Chinese young adult stroke patients[J]. J Stroke Cerebrovasc Dis，2014，23（6）：1519-1523.
[3]中华医学会神经病学分会，中华医学会神经病学分会脑血管病学组. 中国急性缺血性脑卒中诊治指南2018[J]. 中华神经科杂志，2018，51（9）：666-682.
[4]XU Y Y，LI M L，GAO S，et al. Etiology of intracranial stenosis in young patients：a high-resolution magnetic resonance imaging study[J/OL]. Ann Transl Med，2017，5（16）：319[2022-07-26]. http://dx.doi.org/10.21037/atm.2017.06.31.
[5]FAKIH R，ROA J A，BATHLA G，et al. Detection and quantification of symptomatic atherosclerotic plaques with high-resolution imaging in cryptogenic stroke[J]. Stroke，2020，51（12）：3623-3631.
[6]KERNAN W N，OVBIAGELE B，BLACK H R，et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack：a guideline for healthcare professionals from the American Heart Association/American Stroke Association[J]. Stroke，2014，45（7）：2160-2236.
[7]袁伟壮，李明利，冯逢，等. 高分辨磁共振影像在青年卒中的临床诊断价值[J]. 中风与神经疾病杂志，2021，38（11）：984-989.
[8]XU W H，XING Y Q，YAN Z R，et al. Cardiac right-to-left shunt subtypes in Chinese patients with cryptogenic strokes：a multicenter case-control study[J]. Eur J Neurol，2014，21（3）：525-528.
[9]ANDO T，HOLMES A A，PAHUJA M，et al. Meta-analysis comparing patent foramen ovale closure versus medical therapy to prevent recurrent cryptogenic stroke[J]. Am J Cardiol，2018，121（5）：649-655.
[10]CHEN J Z，THIJS V N. Atrial fibrillation following patent foramen ovale closure：systematic review and meta-analysis of observational studies and clinical trials[J]. Stroke，2021，52（5）：1653-1661.
[11]PREFASI D，MARTÍNEZ-SÁNCHEZ P，FUENTES B，et al. The utility of the RoPE score in cryptogenic stroke patients ≤50 years in predicting a stroke-related patent foramen ovale[J/OL]. Int J Stroke，2016，11（1）：NP7-NP8[2022-07-28]. https://doi.org/10.1177/1747493015607505.
[12]YANG X，SUN J，JIA M Y，et al. The value of high-resolution MRI in the diagnosis，efficacy of treatment，and prognosis of central nervous system vasculitis[J]. Folia Neuropathol，2021，59（4）：372-377.
[13]BERLIT P，KRAEMER M. Cerebral vasculitis in adults：what are the steps in order to establish the diagnosis? Red flags and pitfalls[J]. Clin Exp Immunol，2014，175（3）：419-424.
[14]DEBETTE S，LEYS D. Cervical-artery dissections：predisposing factors，diagnosis，and outcome[J]. Lancet Neurol，2009，8（7）：668-678.
[15]MOREL A，NAGGARA O，TOUZÉ E，et al. Mechanism of ischemic infarct in spontaneous cervical artery dissection[J]. Stroke，2012，43（5）：1354-1361.
[16]ENGELTER S T，TRAENKA C，GENSICKE H，et al. Aspirin versus anticoagulation in cervical artery dissection（TREAT-CAD）：an open-label，randomised，non-inferiority trial[J]. Lancet Neurol，2021，20（5）：341-350.
[17]LI S，ZI W J，CHEN J J，et al. Feasibility of thrombectomy in treating acute ischemic stroke because of cervical artery dissection[J]. Stroke，2018，49（12）：3075-3077.
[18]DEBETTE S，COMPTER A，LABEYRIE M A，et al. Epidemiology，pathophysiology，diagnosis，and management of intracranial artery dissection[J]. Lancet Neurol，2015，14（6）：640-654.
[19]M'BAREK L，SAKKA S，MEGHDICHE F，et al. MTHFR（C677T，A1298C），FV leiden polymorphisms，and the prothrombin G20210A mutation in arterial ischemic stroke among young tunisian adults[J]. Metab Brain Dis，2021，36（3）：421-428.
[20]PEZZINI A，DEL ZOTTO E，ARCHETTI S，et al. Plasma homocysteine concentration，C677T MTHFR genotype，and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke[J]. Stroke，2002，33（3）：664-669.
[21]HUO Y，LI J P，QIN X H，et al. Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China：the CSPPT randomized clinical trial[J]. JAMA，2015，313（13）：1325-1335.
[22]RUTTEN-JACOBS L C，LARSSON S C，MALIK R，et al. Genetic risk，incident stroke，and the benefits of adhering to a healthy lifestyle：cohort study of 306 473 UK Biobank participants[J/OL]. BMJ，2018，363：k4168[2022-07-28]. https://doi.org/10.1136/bmj.k4168.
[23]梁萌，左朦，赵娜娜，等. 青年缺血性卒中患者早期不良结局的相关因素分析[J]. 中国脑血管病杂志，2017，14（8）：393-398.
[24]RUTTEN-JACOBS L C，MAAIJWEE N A，ARNTZ R M，et al. Long-term risk of recurrent vascular events after young stroke：the FUTURE study[J]. Ann Neurol，2013，74（4）：592-601.
[25]陈红兵，洪华，刘刚，等. 青年缺血性卒中或短暂性脑缺血发作患者卒中复发风险及其预测因子[J]. 中国脑血管病杂志，2015，12（9）：462-467.
[26]SCHAAPSMEERDERS P，MAAIJWEE N A，VAN DIJK E J，et al. Long-term cognitive impairment after first-ever ischemic stroke in young adults[J]. Stroke，2013，44（6）：1621-1628.
[27]MAAIJWEE N A，ARNTZ R M，RUTTEN-JACOBS L C，et al. Post-stroke fatigue and its association with poor functional outcome after stroke in young adults[J]. J Neurol Neurosurg Psychiatry，2015，86（10）：1120-1126.
[28]MAAIJWEE N A，TENDOLKAR I，RUTTEN-JACOBS L C，et al. Long-term depressive symptoms and anxiety after transient ischaemic attack or ischaemic stroke in young adults[J]. Eur J Neurol，2016，23（8）：1262-1268.
[29]刘晶，王大鹏，王伟娟，等. 青年缺血性脑卒中后抑郁影响因素分析[J]. 现代预防医学，2012，39（5）：1160-1161，1165.
[30]HANNERZ H，HOLBÆK PEDERSEN B，POULSEN O M，et al. A nationwide prospective cohort study on return to gainful occupation after stroke in Denmark 1996-2006[J/OL]. BMJ Open，2011，1（2）：e000180[2022-07-28]. http://dx.doi.org/10.1136/bmjopen-2011-000180.
