Neural Network Mechanisms of Apathy in Cerebral Small Vessel Disease

doi:10.3969/j.issn.1673-5765.2025.07.013

Abstract

Abstract: Apathy is a common neuropsychiatric symptom in cerebral small vessel disease (CSVD), often clinically manifested as decreased goal-directed behavior, cognitive activity, and emotional expression. The occurrence of apathy in CSVD patients may be related to neural network dysfunction and is closely related to cognitive impairment. This article aims to review the neural network mechanisms of apathy in CSVD patients.

Key words: Cerebral small vessel disease; Apathy; Neural network; Mechanism

摘要： 淡漠是脑小血管病（cerebral small vessel disease，CSVD）常见的神经精神症状，临床常表现为目标导向行为减少、认知活动降低及情感表达减少等。CSVD患者淡漠的出现可能与神经网络功能障碍有关，且与认知功能损害存在密切联系。本文旨在对CSVD患者淡漠的神经网络机制进行综述。

关键词: 脑小血管病; 淡漠; 神经网络; 机制

CLC Number:

LI Hua, MA Shangjia, GAO Dewang, LYU Jiayu, YU Wenlong, GUO Xia, WU Li’e. Neural Network Mechanisms of Apathy in Cerebral Small Vessel Disease[J]. Chinese Journal of Stroke, 2025, 20(7): 911-916.

李华, 马尚佳, 高德旺, 吕佳瑜, 于文龙, 郭霞, 吴丽娥. 脑小血管病淡漠的神经网络机制[J]. 中国卒中杂志, 2025, 20(7): 911-916.

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