中国卒中杂志 ›› 2018, Vol. 13 ›› Issue (09): 951-955.DOI: 10.3969/j.issn.1673-5765.2018.09.012

• 专题综述 • 上一篇    下一篇

脑微出血与认知功能障碍相关性研究进展

郎晓岚,苗树川,孙晓培   

  1. 1  116001 大连市友谊医院神经内科
    2  大连医科大学附属一院神经内科
  • 收稿日期:2018-05-18 出版日期:2018-09-20 发布日期:2018-09-20
  • 通讯作者: 孙晓培 sunxiaopei69@163.com

Advance of Correlation of Cerebral Microbleeds and Cognitive Impairment

  • Received:2018-05-18 Online:2018-09-20 Published:2018-09-20

摘要:

关于脑微出血的概念及其与认知功能障碍相关性的研究日益受到关注。近年来,研究的 热点多集中于脑微出血致认知功能下降的机制方面,本文就脑微出血的概念及流行病学、其与认知 障碍的关系以及致认知功能下降的机制方面的研究做一综述,旨在为临床治疗、延缓高危人群的认 知功能衰退提供帮助。

文章导读: 脑微出血数量及分布与认知功能障碍存在相关性,其导致认知功能障碍的分子生物学机制及预测价值尚无定论。

关键词: 脑微出血; 认知功能障碍; 发病机制

Abstract:

More and more attention is paid to the concept of cerebral microbleeds (CMBs) and the research on correlation between CMBs and cognitive impairment. In recent years, most research focused on the mechanism of cognitive impairment caused by CMBs. This article reviewed the concept and epidemiology of CMBs, the relationship of CMBs and cognitive dysfunction, and the mechanism of cognitive dysfunction caused by CMBs, with the aim to provide reference in treating and delaying cognitive decline of high-risk patients.

Key words: Cerebral microbleeds; Cognitive impairment; Pathogenic mechanism