脑缺血再灌注后神经可塑性的研究进展

摘要/Abstract

摘要：

【摘要】大脑对缺血再灌注损伤有一定代偿修复能力，可通过多种机制发生可塑性变化。脑内与缺血再灌注有关的可塑性物质主要有突触素（synaptophysin，Syn）、生长相关蛋白-43（growthassociated protein-43，GAP-43）及微管相关蛋白-2（microtubule-associated protein-2，MAP-2）等物质，它们通过各自途径影响脑缺血再灌注后脑的可塑性变化，而可塑性变化又受到生存环境、康复训练、药物治疗等因素的影响。

关键词: 缺血再灌注; 可塑性

Abstract:

【Abstract】 The brain has a capacity of repairing ischemia reperfusion injury. Through various mechanisms, the brain develops a plastically change. The plastically substances of the internal brain which is related to ischemia reperfusion injury are mainly the followings: synaptophysin(Syn),growth-associated protein-43(GAP-43) and microtubule-associated protein-2(MAP-2), etc. By kinds of means, they infect the plastically change of ischemia reperfusion injury respectively. But the change is also influenced by factors such as the living surroundings, rehabilitation training and pharmacotherapy, etc.

Key words: Ischemia-reperfusion; Plasticity

刘成勇1，徐鸣曙1，葛林宝2. 脑缺血再灌注后神经可塑性的研究进展[J]. 卒中杂志.

LIU Cheng-Yong*, XU Ming-Shu, GE Lin-Bao.. Advances of Research on Neuronal Plasticity after Cerebral Ischemia-Reperfusion[J]. Chinese Journal of Stroke.

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