前循环颅内外动脉狭窄与认知功能障碍

doi:10.3969/j.issn.1673-5765.2017.11.010

摘要/Abstract

摘要：

前循环颅内外动脉狭窄是缺血性卒中危险因素之一，目前研究证实前循环颅内外动脉狭窄可以通过多种机制引起认知功能下降。其治疗方法有药物治疗、介入治疗及手术治疗。本文对前循环颅内外动脉狭窄引起认知功能障碍的机制、临床表现及治疗方法进行综述，为临床工作者提供参考。

文章导读： 前循环颅内外动脉狭窄可能通过共病因素、低灌注、引发脑梗死等机制导致患者的认知功能障碍。因入组标准和评价标准不一致，目前关于药物、介入、动脉内膜剥脱术、颅内外动脉搭桥术等治疗方式对认知障碍的影响尚无定论。

关键词: 前循环; 颅内外动脉狭窄; 认知功能障碍; 颈动脉支架成形术; 颈动脉内膜剥脱术; 血运重建

Abstract:

Anterior circulation intra- and extracranial artery stenosis is one of the risk factors for ischemic stroke. Recent research had proven that anterior circulation intra- and extracranial artery stenosis might cause cognitive function decline through a variety of mechanism. Its treatment methods included drug therapy, interventional therapy and surgical treatment.This paper reviewed the mechanism of cognitive impairment caused by anterior circulation intra- and extracranial artery stenosis, and its clinical manifestation and treatment, so as to provide reference for clinical work.

Key words: Anterior circulation; Intra- and extracranial artery stenosis; Cognitive impairment;
Carotid artery stenting; Carotid endarterectomy; Revascularization

邱利君，经屏. 前循环颅内外动脉狭窄与认知功能障碍[J]. 中国卒中杂志, 2017, 12(11): 1023-1032.

QIU Li-Jun,JING Ping. Anterior Circulation Intra- and extracranial Artery Stenosis and Cognitive Impairment[J]. Chinese Journal of Stroke, 2017, 12(11): 1023-1032.

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