关键词: 短暂性脑缺血发作; 肢体抖动; 大动脉狭窄

Abstract:

Objective To summarize the clinical characteristics and pathogenesis of limb-shaking transient ischemic attack (LS-TIA) in elderly patients, and to provide reference for clinicians. 

Methods The general clinical data and treatment regimen of 21 LS-TIA elderly patients in Wuhu hospital from January 2013 to June 2017 were collected, and a retrospective analysis was performed to summarize the clinical characteristics of LS-TIA. 

Results All of the 21 elderly patients presented with unilateral limb transient and uncontrollable involuntary shaking. All patients had contralateral intracranial and/or extracranial arteries severe stenosis or occlusion diagnosed by MRI+DWI+MRA examination. All patients were given antiplatelet and intensive statin therapy, proper control of blood pressure and treatment of primary diseases. After the treatment, clinical symptoms of all patients were alleviated, and no TIA and other cerebrovascular events occurred during the follow-up. 

Conclusions LS-TIA should be considered when occurring unilateral limb paroxysmal shaking. In general, LS-TIA patients have contralateral intracranial and/or external arteries stenosis or occlusion, and these patients should be given aggressive stroke secondary prevention.

Key words: Transient ischemic attack; Limb shake; Large artery stenosis