关键词: 缺血型烟雾病; 高压氧; 护理; 不良反应

Abstract:

Objective To observe the effect of nursing in hyperbaric oxygen (HBO) in children with ischemic moyamoya disease. Methods This retrospective analysis enrolled the children with ischemic moyamoya disease (aged 1 to 16 years old) who were admitted to Department of Hyperbaric Oxygen of Beijing Tiantan Hospital from September 2012 to August 2019. Based on the date of starting HBO nursing in September 2015, all the patients were divided into control group and nursing group. Good prognosis was defined as a mRS score of 0 to 2. The difference in the percentage of completing HBO treatment ≥5 times, adverse reaction, and the percentage of 90-day good prognosis in children who had completed HBO treatment ≥5 times between the two groups were compared. Results A total of 84 cases were included in this analysis. Nursing group: 48 cases, 25 males, 23 females, the age range of 3 to 16 years, and the mean age of 8.81±3.83 years; control group: 36 cases, 18 males, 18 females, the age range of 2 to 16 years, and the mean age of 9.50±3.60 years. The proportion of patients who completed ≥5 times of HBO treatment in nursing group was higher than that in control group (97.9% vs 83.3%, P =0.02). No patients in both two groups suffered from adverse reaction such as barometric injury, decompression sickness, oxygen toxicity and so on during HBO treatment. 47 cases in nursing group and 30 cases in control group completed ≥5 times of HBO treatment, and they in the two groups had no statistical difference in 90-day good prognosis rate (nursing vs control group: 63.83% vs 60.00%, P =0.60). Conclusions Hyperbaric oxygen nursing can help improve HBO treatment compliance in children with ischemic moyamoya disease, while no improvement in 90-day functional prognosis was observed.

Key words: Ischemic moyamoya disease; Hyperbaric oxygen; Nursing; Adverse reaction