卵圆孔未闭相关性卒中的诊治研究进展

doi:10.3969/j.issn.1673-5765.2021.09.014

摘要/Abstract

摘要： 卵圆孔未闭（patent f oramen o vale，PFO）与卒中发病有明显的关联。应利用卒中高风险 PFO解剖学特征、卒中影像特征及反常栓塞风险量表等，经多科综合评估，选择患者最适合的治疗方案。多数现有研究及指南支持对于卒中高风险PFO患者，首选PFO封堵术加术后长期抗血小板治疗；单独抗凝治疗与单独抗血小板治疗在预防卒中复发上同效。

文章导读： PFO与隐源性卒中的发生及复发密切相关，经多科综合评估后，高风险PFO宜首选封堵治疗。

关键词: 卵圆孔未闭; 隐源性卒中; 心源性卒中; 封堵术

Abstract: Patent foramen ovale (PFO) is strongly associated with cryptogenic stroke. For the patients with high-risk PFO, the appropriate treatment is decided by comprehensive evaluation including the high-risk PFO anatomical features, stroke imaging features and risk of paradoxical embolism (RoPE) scale, etc. Most of the existing research and guidelines support that PFO closer plus long-term antiplatelet therapy should be preferred for the patients with high-risk PFO, but the postoperative complications such as atrial fibrillation and occluder-related thrombosis may occur. Anticoagulation therapy and antiplatelet therapy are equally effective in preventing recurrent stroke.

Key words: Patent foramen ovale; Cryptogenic stroke; Cardiogenic stroke; Closure

王泽祎, 杨亭亭, 刘广志. 卵圆孔未闭相关性卒中的诊治研究进展[J]. 中国卒中杂志, 2021, 16(09): 960-966.

WANG Ze-Yi, YANG Ting-Ting, LIU Guang-Zhi. Progress in Diagnosis and Treatment of Stroke Related with Patent Foramen Ovale[J]. Chinese Journal of Stroke, 2021, 16(09): 960-966.

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