1 Silverman IE，Restrepo L，Mathews GC. Post-stroke

seizures[J]. Arch Neurol，2002，59：195-201.

2 Fisher RS，Acevedo C，Arzimanoglou A，et a1.

ILAE official report：a practical clinical definition of

epilepsy[J]. Epilepsia，2014，55：475-482.

3 中华医学会神经病学分会，中华医学会神经病学分

会脑血管病学组. 中国急性缺血性脑卒中诊治指南

2014[J]. 中华神经科杂志，2015，48：246-257.

4 Arntz RM，Rutten-Jacobs LC，Maaijwee NA，et

al. Post-stroke epilepsy is associated with a high

mortality after a stroke at young age：follow-up of

transient ischemic attack and stroke patients and

unelucidated risk factor evaluation study[J]. Stroke，

2015，46：2309-2311.

5 Conrad J，Pawlowski M，Dogan M，et al. Seizures

after cerebrovascular events：risk factors and clinical

features[J]. Seizure，2013，22：275-282.

6 Chadehumbe MA，Khat r i P，Khoury JC，et al.

Seizures are common in the acute setting of childhood

stroke：a population-based study[J]. J Child Neurol，

2009，24：9-12.

7 Kopyta I，Sarecka-Hujar B，Skrzypek M. Post-stroke

epilepsy in Polish paediatric patients[J]. Dev Med

Child Neurol，2015，57：821-828.

8 Awada A，Omojola MF，Obeid T. Late epileptic

seizures after cerebral infarction[J]. Acta Neurol

Scand，1999，99：265-268.

9 De Reuck JL. Stroke-related seizures and epilepsy[J].

Neurol Neurochir Pol，2007，41：144-149.

10 Dachet F，Bagla S，Keren-Aviram G，et al. Predicting

novel histopathological microlesions in human

epileptic brain through transcriptional clustering[J].

Brain，2015，138：356-370.

11 Gilad R，Lampl Y，Eilam A，et al. SPECT-DTPA as

a tool for evaluating the blood–brain barrier in poststroke

seizures[J]. J Neurol，2012，259：2041-2044.

12 Lei Z，Zhang H，Liang Y，et al. Reduced expression

of IA channels is associated with postischemic

seizures in hyperglycemic rats[J]. J Neurosci Res，

2014，92：1775-1784.

13 K h a r l amo v EA，Kha r l amov A，Ke l l y KM.

Changes in neuropeptide Y protein expression

following photothrombotic brain infarction and

epileptogenesis[J]. Brain Res，2007，1127：151-162.

14 Liu J，Schmitt KL，Kharlamov EA，et al. Quantitative

reverse transcription-polymerase chain reaction of

GABA(A) alpha1，beta1 and gamma2S subunits in

epileptic rats following photothrombotic infarction of

neocortex[J]. Epilepsy Res，2002，52：85-95.

15 Zhang B，Chen M，Yang H，et al. Evidence for

involvement of the CD40/CD40L system in poststroke

epilepsy[J]. Neurosci Lett，2014，567：6-10.

16 Yang H，Song Z，Yang GP，et al. The ALDH2

rs671 polymorphism affects post-stroke epilepsy

susceptibility and plasma 4-HNE levels[J]. PloS One，

2014，9：e109634.

17 De Reuck J，Van Maele G. Status epilepticus in stroke

patients[J]. Eur Neurol，2009，62：171-175.

18 Graham NS，Crichton S，Koutroumanidis M，et al.

Incidence and associations of Post-stroke epilepsy：the

prospective South London Stroke Register[J]. Stroke，

2013，44：605-611.

19 Hundozi Z，Shala A，Boshnjaku D，et al. Hypertension

on admission is associated with a lower risk of early

seizures after stroke[J]. Seizure，2016，36：40-43.

20 Zhang C，Wang X，Wang Y，et al. Risk factors for

post-stroke seizures：a systematic review and metaanalysis[

J]. Epilepsy Res，2014，108：1806-1816.

21 Ferro JM，Correia M，Rosas MJ，et al. Seizures

in cerebral vein and dural sinus thrombosis[J].

Cerebrovasc Dis，2003，15：78-83.

22 Mi si rl i H，Ozge A，Somay G，et a l. Seizure

development after stroke[J]. Int J Clin Pract，2006，60：

1536-1541.