Pathogenesis, Imaging Features and Natural Course of Intracranial Artery Dissection

doi:10.3969/j.issn.1673-5765.2020.10.007

Abstract

Abstract:

Compared to extracranial artery dissection, intracranial artery dissection (IAD) is relatively uncommon, IAD clinical manifestations lack specificity, and it can present with either ischemic or hemorrhagic events. Artery dissection mostly occurs in young people. Due to the different location, formation timing and lesions severity, IAD clinical manifestations are various, and imaging is the key for the diagnosis of artery dissection. The recurrence rate and mortality of IAD are relatively high. IAD patients with no or mild symptoms can be given conservative treatment or follow-up observation, and patients with severe symptoms or progressive artery dissection should be given active treatment, including endovascular treatment.

Key words: Intracranial artery dissection; Pathogenesis; Imaging; Natural course

摘要：

颅内动脉夹层相比颅外动脉夹层较少见，且临床表现缺乏特异性，既可以表现为缺血性事件，也可以表现为出血性事件，多发生于年轻人。由于夹层发生部位、形成时机以及病变严重程度不同，临床表现各种各样，影像学对于确诊动脉夹层至关重要。颅内动脉夹层易复发，且死亡率较高，除无症状或症状轻微的患者给予保守治疗或随访观察外，对于症状较重或进展性动脉夹层患者，应给予积极治疗，包括血管内治疗。

关键词: 颅内动脉夹层; 发病机制; 影像学; 自然病程

LI Jie, HE Xiong-Jun,LI Kai-Feng, HU Ming, ZHANG Liang, ZHOU Hong-Xing, WANG Ze-Qun, WANG Yi-Fan, LIU Ya-Jie. Pathogenesis, Imaging Features and Natural Course of Intracranial Artery Dissection[J]. Chinese Journal of Stroke, 2020, 15(10): 1067-1072.

黎杰，贺雄军，黎凯锋，胡明，张亮，周宏星，王泽群，王一凡，刘亚杰. 颅内动脉夹层的发病机制、影像学特点和自然病程[J]. 中国卒中杂志, 2020, 15(10): 1067-1072.

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