Chinese Journal of Stroke ›› 2022, Vol. 17 ›› Issue (04): 418-425.DOI: 10.3969/j.issn.1673-5765.2022.04.017
Previous Articles Next Articles
Received:
2021-11-26
Online:
2022-04-20
Published:
2022-04-20
张冬雪, 邹伟
基金资助:
ZHANG Dongxue, ZOU Wei. Progress and Mechanism of Exosome in Ischemic Stroke[J]. Chinese Journal of Stroke, 2022, 17(04): 418-425.
张冬雪, 邹伟. 外泌体对缺血性卒中的作用机制及研究进展[J]. 中国卒中杂志, 2022, 17(04): 418-425.
[1] Global Burden of Disease Study 2013 Collaborators. Global,regional,and national incidence,prevalence,and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries,1990-2013:a systematic analysis for the global burden of disease study 2013[J]. Lancet,2015,386(9995):743-800. [2] CAMPBELL B C V,KHATRI P. Stroke[J]. Lancet,2020,396(10244):129-142. [3] ZHANG L,ZHANG Z G,CHOPP M. T he neurovascular unit and combination treatment strategies for stroke[J]. Trends Pharmacol Sci,2012,33(8):415-422. [4] BOESE A C,LE Q E,PHAM D,et al. Neural stem cell therapy for subacute and chronic ischemic stroke[J/OL]. Stem Cell Res Ther,2018,9(1):154[2021-11-15]. https://doi.org/10.1186/s13287-018-0913-2. [5] BUDNIK V,RUIZ-CAÑADA C,WENDLER F. Extracellular vesicles round off communication in the nervous system[J]. Nat Rev Neurosci,2016,17(3):160-172. [6] NOZOHOURI S,VAIDYA B,ABBRUSCATO T J. Exosomes in ischemic stroke[J]. Curr Pharm Des,2020,26(42):5533-5545. [7] 蔡利,陈湘闻,徐胜波. 细胞外囊泡在缺血性脑卒中中的研究进展[J]. 卒中与神经疾病,2021,28(2):214-217. [8] VAN NIEL G,D’ANGELO G,RAPOSO G. Shedding light on the cell biology of extracellular vesicles[J]. Nat Rev Mol Cell Biol,2018,19(4):213-228. [9] PAN B T,JOHNSTONE R M. Fate of the transferrin receptor during maturation of sheep reticulocytes,invitro:selective externalization of the receptor[J]. Cell,1983,33(3):967-978. [10] JOHNSTONE R M,ADAM M,HAMMOND J R,et al. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles(exosomes)[J]. J Biol Chem,1987,262(19):9412-9420. [11] TKACH M,THÉRY C. Communication by extracellular vesicles:where we are and where we need to go[J]. Cell,2016,164(6):1226-1232. [12] HESSVIK N P,LLORENTE A. Current knowledge on exosome biogenesis and release[J]. Cell Mol Life Sci,2018,75(2):193-208. [13] BATAGOV A O,KUROCHKIN I V. Exosomes secreted by human cells transport largely mRNA fragments that are enriched in the 3'-untranslated regions[J/OL]. Biol Direct,2013,8:12[2021-11-15].https://doi.org/10.1186/1745-6150-8-12. [14] COCUCCI E,MELDOLESI J. Ectosomes and exosomes:shedding the confusion between extracellular vesicles[J]. Trends Cell Biol,2015,25(6):364-372. [15] VALADI H,EKSTROM K,BOSSIOS A,et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells[J]. Nat Cell Biol,2007,9(6):654-659. [16] ARENACCIO C,FEDERICO M. The multifaceted functions of exosomes in health and disease:an overview[J/OL]. Adv Exp Med Biol,2017,998:3-19[2021-11-15]. https://doi.org/10.1007/978-981-10-4397-0_1. [17] JIANG X C,GAO J Q. Exosomes as novel biocarriers for gene and drug delivery[J]. Int J Pharm,2017,521(1/2):167-175. [18] 王霞,朱敏霞,韩峰. 外泌体在脑卒中病理过程中的作用及机制研究[J]. 中国现代应用药学,2018,35(7):1095-1101. [19] VIJAYAN M,REDDY P H. Peripheral biomarkers of stroke:focus on circulatory microRNAs[J]. Biochim Biophys Acta,2016,1862(10):1984-1993. [20] WANG J. Preclinical and clinical research on inflammation after intracerebral hemorrhage[J]. ProgNeurobiol,2010,92(4):463-477. [21] 马雪寒,陈丽霞. 脑梗死后miR-17-92簇修复神经血管单元的研究进展[J]. 脑与神经疾病杂志,2021,29(2):130-133.
[22] 龙小兵. 星形胶质细胞外泌体携带的miR-873a-5p对创伤性颅脑损伤中小胶质细胞表型和功能的调控作用与机制研究[D]. 武汉:华中科技大学,2020.
[53] JIANG C,HOU B R,WANG Z N,et al. How neural stem cells promote the repair of brain injury through immunoregulation[J]. Chin Med J(Engl),2020,133(19):2365-2367.
[55] VOGEL A,UPADHYA R,SHETTY A K. Neural stem cell derived extracellular vesicles:Attributes and prospects for treating neurodegenerative disorders[J/OL]. EBioMedicine,2018,38:273-282[2021-11-15] . ht t p s : //doi .org /10.1016/j.ebiom.2018.11.026. |
[1] | WU Yuqian, ZHANG Yumei, FAN Xiaowei, WANG Anxin, PANG Wenbin. The Efficacy of Kinesthetic Motor Imagery Therapy for Hand Function Rehabilitation of Stroke Patients [J]. Chinese Journal of Stroke, 2022, 17(12): 1366-1371. |
[2] | YI Luo, ZHOU Hongyu, QIU Xin, LI Zixiao, WANG Yongjun. DNA Methylation Changes in Atherosclerotic Diseases [J]. Chinese Journal of Stroke, 2022, 17(11): 1163-1170. |
[3] | WANG Yubo, LI Zixiao, WANG Yongjun. Progress of the Relationship between Epigenetics and Oxidative Stress after Ischemic Stroke [J]. Chinese Journal of Stroke, 2022, 17(11): 1171-1177. |
[4] | CUI Lingyun, QIU Xin, ZHOU Hongyu, LI Zixiao, WANG Yongjun. Progress of the Relationship between DNA Methylation and Type 2 Diabetes [J]. Chinese Journal of Stroke, 2022, 17(11): 1183-1188. |
[5] | DENG Yuhan, LIU Shuang, WANG Ziyao, WANG Yuxin, LIU Baohua. The Effect of Machine Learning Model for Predicting Stroke Risk in the General Population Based on Structured Data: A Systematic Review and Meta-Analysis [J]. Chinese Journal of Stroke, 2022, 17(11): 1189-1197. |
[6] | LIU Guangliang, HAN Kaiyue, SU Wenlong, ZHANG Hao. Effects of Aerobic Cycling Training Intensity on Motor and Cardiopulmonary Fitness in Patients with Ischemic Stroke [J]. Chinese Journal of Stroke, 2022, 17(11): 1203-1208. |
[7] | XU Yingxin, ZHANG Shuang, ZHOU Xiaomei, YUAN Jinglin, ZHAO Liuzhuang, YANG Haihua. Correlation of Non-Stenotic Carotid Plaque with Anterior Circulation Embolic Stroke of Undetermined Source [J]. Chinese Journal of Stroke, 2022, 17(11): 1233-1237. |
[8] | CHENG Shi, LI Jing, GUO Junping, HU Aixiang, YU Xinwei, HAN Wei, LIANG Ying, ZHANG Yuewei, JI Ruijun. Clinical Characteristics and Risk Factors of Infection in Patients with Acute Stroke during Hospitalization [J]. Chinese Journal of Stroke, 2022, 17(10): 1065-1070. |
[9] | XIANG Wei, XU Luyao, ZHANG Manman, WEI Hongchun, LIANG Zhigang. The Frequency and Influencing Factors of Asymmetrical Prominent Veins Sign on Susceptibility-Weighted Imaging in Acute Ischemic Stroke [J]. Chinese Journal of Stroke, 2022, 17(10): 1097-1102. |
[10] | ZHAO Yongrui, LIU Zhanhui. Progress of Diffusion Tensor Imaging in Evaluating Motor Function Prognosis of Patients with Ischemic Stroke [J]. Chinese Journal of Stroke, 2022, 17(10): 1114-1119. |
[11] | ZHANG Boyu, GUO Yucheng, CUI Yuxia, LI Yingli, LYU Yumei. Seeking Medical Services Decision-Making Status and Relevant Influencing Factors in Patients with Acute Ischemic Stroke: A Review [J]. Chinese Journal of Stroke, 2022, 17(10): 1127-1132. |
[12] | WU Tingting, LIU Yafei, YAN Shixi, WU Yiping, ZHANG Zhongbo, ZAHNG Hanfei, FANG Pinping. Application of “Internet Plus” in Emergency Care of Acute Ischemic Stroke [J]. Chinese Journal of Stroke, 2022, 17(10): 1133-1138. |
[13] | ZHANG Yige, ZHANG Wan, ZHANG Luyang, WANG Xin, DING Lan, WANG Yuying, PEI Lulu, FANG Hui, XU Yuming, SONG Bo. Association of Artery Occlusion and Recurrent Ischemic Stroke Related with Cerebral Artery Dissection [J]. Chinese Journal of Stroke, 2022, 17(09): 932-936. |
[14] | LYU Wei, WANG Anxin, TIAN Xue, ZHANG Xiaoli, XU Yuyuan, MENG Xia. Effect of Xinxuening Capsule on Short-term Functional Outcome in Patients with Ischemic Stroke and High Homocysteine Level [J]. Chinese Journal of Stroke, 2022, 17(09): 972-976. |
[15] | ZHANG Xinmiao, PAN Yuesong, XIANG Xianglong, WANG Yongjun, MENG Xia. Early Clinical Pathway Intervention to Improve the Key Performance Indicators of Medical Care for Ischemic Stroke [J]. Chinese Journal of Stroke, 2022, 17(09): 977-984. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||