Abstract: Objective  To analyze the completion condition of general projects in the field of cerebrovascular diseases of National Natural Science Foundation of China, and discuss the status and existing problems of basic research in this field. Predict the development trend and provide reference for decision-making.
Methods  Through the big data knowledge management service portal of the National Natural Science Foundation of China, the basic information of the concluding projects with application code H0906 (cerebrovascular structure, function abnormalities and related diseases) during 2019 to 2021 were obtained. Excel software and Power Query components were used to analyze the research achievements, supporting institution distribution, regional distribution and research direction distribution of the concluding project, and VOSviewer software was used to analyze research hotspots. 
Results  There were 177 concluding projects with code H0906 during 2019 to 2021, supported by 51 institutions (14 of which undertook 110 projects, 62.15%). 1532 academic papers were produced and 324 talents were cultivated. Among the supporting institutions, comprehensive colleges and universities undertook 96 projects (54.24%), and each project produced 9.52 academic papers, with 1.91 papers more than that from medical colleges and universities. Among the supporting institutions from 19 provinces and cities, Shanghai, Jiangsu, Beijing, Guangdong, Hubei, Chongqing 6 provinces and cities completed 113 projects (63.84%), the number of authorized patents was 30 (90.91%), and 27 person-time participated in international conferences (75.00%). There were 18 research directions under H0906, involving 107 projects of ischemic cerebrovascular diseases (60.45%). Keyword cluster analysis showed that the basic research hotspots in the field of cerebrovascular diseases were inflammatory response, microglia, neuroprotection and nerve regeneration.
Conclusions  Research achievements of general projects in the field of cerebrovascular diseases of National Natural Science Foundation of China were of various types, were mainly papers and talent training, supported by comprehensive colleges and universities with unbalanced geographical distribution, and research directions were relatively concentrated, which were mainly ischemic cerebrovascular diseases.

Key words: Cerebrovascular disease; National Natural Science Foundation of China; General project; Conclusion; Research achievement

摘要： 目的 分析国家自然科学基金脑血管病领域面上项目结题情况，探讨该领域研究现状和存在问题，预测发展趋势，为决策提供参考。
方法 通过国家自然科学基金大数据知识管理服务门户网站获得2019—2021年申请代码为H0906（脑血管结构、功能异常及相关疾病）结题面上项目的基本信息，采用Excel软件、Power Query组件对结题项目的成果产出、依托单位分布、地域分布、研究方向分布进行分析，使用VOSviewer软件对研究热点进行分析。 
结果 2019—2021年申请代码为H0906的结题项目有177项，依托于51家单位（其中14家承担110项，占62.15%），产出学术论文1532篇，培养人才324名。依托单位中综合类院校承担96项（54.24%），每项产出论文9.52篇，较医科类院校多1.91篇。依托单位所属19个省（直辖市），其中上海市、江苏省、北京市、广东省、湖北省、重庆市等6省（直辖市）结题113项（63.84%），授权专利数30项（90.91%），参加国际会议27人次（75.00%）。H0906下设18个研究方向，涉及缺血性脑血管病研究107项（60.45%）。关键词聚类分析显示，脑血管病领域基础研究热点是炎性反应、小胶质细胞、神经保护及神经再生等。
结论 国家自然科学基金脑血管病领域面上项目成果产出类型多样，以论文和人才培养为主，依托单位以综合性院校为主，地域分布不均衡，研究方向相对集中，以缺血性脑血管病为主。

关键词: 脑血管病; 国家自然科学基金; 面上项目; 结题; 研究成果