Abstract: Cerebrovascular events are believed to be related to carotid atherosclerotic plaque.Focal hemodynamics has a prominent impact on the initiation and development of carotid plaque.Many factors, such as carotid bifurcations, pulsatile flow conditions and arterial geometries, havebeen proposed as important factors to focal hemodynamics mechanism. Plaque stenosis may set uphemodynamic conditions causing distal arterial wall collapse.

Key words: Carotid artery; Plaque; Hemodynamics

摘要： 颈动脉粥样硬化性斑块与卒中有着密切的关系，局部血液动力学对颈动脉粥样硬化性斑块的形成和性质有重要影响。影响局部血液动力学的因素有颈动脉分叉结构、颈动脉三维结构及血流脉动等。另外，斑块造成狭窄后，引起远端血管的血液动力学的改变，破坏远端管壁结构。

关键词: 颈动脉; 斑块; 血液动力学