›› 2012, Vol. 7 ›› Issue (07): 543-548.

• 论著 • Previous Articles     Next Articles

Preoperative Prediction of Postoperative Death for the Minimally Invasive Hematoma Aspiration and Thrombolysis of Intracerebral Hemorrhage

XU Feng, TANG Zhou-Ping, ZHUWen-Hao, et al   

  • Received:2011-08-26 Revised:2011-07-26 Online:2012-07-20 Published:2012-07-20
  • Contact: ZHU Sui-Qiang

脑出血微创幕上血肿抽吸引流术后死亡风险的术前评估

许峰,唐洲平,朱文浩,唐坤,刘建林,康慧聪,刘晓艳,朱遂强   

  1. 武汉华中科技大学同济医学院附属同济医院神经内科
  • 通讯作者: 朱遂强

Abstract: Objective To predict and estimate the postoperative 30-day mortality for the minimally invasivehematoma aspiration and thrombolysis of intracerebral hemorrhage(ICH) by using the preoperativeclinical date.Methods From Oct. 2005 to Mar. 2009, the initial date and 30-day postoperative outcome of 138ICH cases treated with minimally invasive hematoma aspiration and thrombolysis were collected toinvestigate the risk factors for the postoperative mortality by using logistic regression analysis.Results Among the 138 patients with intracerebral hemorrhage, 28 cases died within 30 daysfollowing the micro-invasive surgery with the mortality of 20.3%. Logistic regression analysisdemonstrated the level of preoperative consciousness be the major risk factor affecting thepostoperative mortality(OR 2.819, 95%CI 1.292-2.133, P <0.001).Conclusion The level of preoperative consciousness is a major source to predict the risk ofpostoperative death for the minimally invasive hematoma aspiration and thrombolysis of ICH.

Key words: intracerebral hemorrahge; micro-invasive surgery; risk factor; prognosis

摘要: 目的 根据患者术前临床特征对行脑出血微创颅内血肿抽吸引流术后30 d内患者的死亡风险进行预测和评估。方法 回顾性的收集自2005年10月~2009年3月在我科行微创颅内血肿抽吸引流术治疗的138例幕上脑出血患者的基线信息和术后30 d临床结局,利用Logistic回归模型,探寻影响术后30 d患者死亡风险的危险因素。结果 138例脑出血患者中,术后30 d内死亡28例,病死率为20.3%。多因素分析显示,仅有术前格拉斯哥意识障碍评分(Glasgow Coma Scale,GCS)(≤8)是影响微创术后患者死亡的主要因素[比值比(odds ratio,OR)2.819,95%可信区间(confidence interval,CI)1.289~6.166,P<0.001]。结论 意识水平是微创术前评估患者术后死亡风险的重要依据。

关键词: 脑出血; 微创术; 危险因素; 预后