Abstract:

Cerebral autoregulation (CA) refers to the inherent ability to maintain the cerebral blood flow stable despite fluctuation in arterial blood pressure or cerebral perfusion pressure. An intact CA helps to avoid brain tissue from neither hyper- nor hypoperfusion. CA is impaired in hemorrhagic stroke in various extents and relates with clinical factors and outcome. CA assessment could not only evaluate clinical prognosis but also render more information in the management of blood pressure and cerebral perfusion pressure. In this review, we aim to target on CA status and its clinical application in hemorrhagic stroke, mainly involving intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH).

Key words: Cerebral autoregulation; Intracerebral hemorrhage; Subarachnoid hemorrhage

摘要：

脑血流自动调节 （cerebral autoregulation， CA） 是人体在一定血压或脑灌注压波动范围内维持脑血流量 （cerebral blood flow） 相对稳定的能力， 可避免脑组织发生高灌注或低灌注。 CA在出血性卒中中存在不同程度受损， 且与临床因素及预后密切相关。 对出血性卒中患者行CA监测不仅可评估临床预后， 还可为动脉血压及脑灌注压的管理提供参考信息。 本文主要就脑出血 （intracerebral hemorrhage， ICH） 和蛛网膜下腔出血 （subarachnoid hemorrhage， SAH） 的CA相关进展做一综述， 旨在探讨CA在上述疾病中的改变及其临床应用价值。

关键词: 脑血流自动调节; 脑出血; 蛛网膜下腔出血