Table of Content

20 December 2016, Volume 11 Issue 12

Previous Issue    Next Issue

Assuming an Important Mission

WANG Yong-Jun

2016, 11(12):  1005-1006.  DOI: 10.3969/j.issn.1673-5765.2016.12.001

Asbtract ( )   PDF (1913KB) ( )  

Related Articles | Metrics

Rethoughts about Diagnosis and Treatment of Post-Stroke Neurogenic Bladder

WANG Yi

2016, 11(12):  1007-1009.  DOI: 10.3969/j.issn.1673-5765.2016.12.002

Asbtract ( )   PDF (1716KB) ( )  

References | Related Articles | Metrics

Discussion about Intermittent Catheterization Combined with Biofeedback Electrical Application for Treatment of Early Urinary Retention after Cerebral Infarction

FENG Jun-Duo,HUANG Li-Juan, WANG Yi

2016, 11(12):  1010-1013.  DOI: 10.3969/j.issn.1673-5765.2016.12.003

Asbtract ( )   PDF (2351KB) ( )  

References | Related Articles | Metrics

Objective To observe the cerebral infarction after urinary retention in patients with urinary flow dynamics related indicators of changes and investigate the intermittent catheterization combined with biofeedback electrical stimulation treatment effectiveness and mechanism of action. Methods A total of 98 patients with acute cerebral infarction with urinary retention were selected from January 2014 to January 2016. General inspection was performed on all patients. The patients were divided into treatment group (n =48) and control group (n =50) according to patients and/or the wishes of the families. The control group received sterile intermittent catheterization combined with bladder function training treatment. The treatment group received biological feedback electric stimulation therapeutic instrument based on the treatment of control group. Two groups were measured at the time of one week before and after treatment respectively, including subjective life quality of 1 W (SQLP) and urine flow dynamics. Results Either group of urinary retention was gradually improved. The self-voiding time of treatment group after treatment for 7 times was earlier than that of the control group (P <0.01). The bladder capacity, residual urine volume and maximum urinary flow rate of treatment group were better than control group (P <0.01). Conclusion Intermittent catheterization combined with biofeedback and electrical stimulation could better improve status of urinary retention at early stage after cerebral infarction.

The Research on Correlation between Lower Urinary Tract Dysfunction and Post-stroke Anxiety Disorder in Acute Stroke Patient

WEI Xiang-Yang, HE Chun-Yan, WANG Ming-Li, et al.

2016, 11(12):  1014-1018.  DOI: 10.3969/j.issn.1673-5765.2016.12.004

Asbtract ( )   PDF (2342KB) ( )  

References | Related Articles | Metrics

Objective To investigate the association between lower urinary tract dysfunction and anxiety disorder in stroke patients through sites of the stroke and the characteristics of bladder urodynamic. Methods The stroke patients were selected and enrolled according to the revised diagnostic criteria by the 4th National Cerebral Vascular Academic Conference. The patients were divided into groups according to sites of stroke. The Self-rating Anxiety Scale (SAS) and urination log were recorded. The association between incidence of anxiety disorders and urination disorder were analyzed. The morbidity rate of frontal lobe injury were calculated statistically. Results The lower urinary tract dysfunction occurrence rate of the frontal stroke group was 1.75 times higher than that of non-frontal stroke group, and the occurrence rate of PSAD in the frontal stroke group was 2.16 times higher than that of non-frontal stroke group. LUTD prevalence increased significantly in patients with PSAD, and urodynamics test prompted that the bladder activity was significantly higher. Conclusion Anxiety disorders and urination disorder after stroke are relatively common and the incidence of frontal stroke is significantly higher, with urination disorder at urine storing stage as the majority. The senior cerebral function, daily life ability, mood after stroke, etc are associated on patients with abnormal urination. Urodynamic changes are mostly caused by overactive activity of bladder and the symptoms are not in consistence with urodynamic manifestation. The test should be done when necessary for further treatment.

Effect Analysis and Risk Evaluation of Hyperbaric Oxygen Therapy on Hemorrhagic Moyamoya Disease in Adult

WANG Xia, DAI Wei

2016, 11(12):  1019-1022.  DOI: 10.3969/j.issn.1673-5765.2016.12.005

Asbtract ( )   PDF (2319KB) ( )  

References | Related Articles | Metrics

Objective To investigate the effect of hyperbaric oxygenation therapy (HBOT) after hemorrhagictype Moyamoya disease (hMMD) in adult and treatment-related risk factors. Methods A total of 41 adult patients with hMMD admitted from 2010 to 2015 were prospectively studied. The patients were divided into HBOT group (21 cases) and control group (20 cases). Modified Rankin Scale (mRS) of neurologic assessments were performed on the 90th day after onset. The effects and related risks of two groups were compared. Logistic regression analysis was used to analyze the risk factors of treatment effect. Results mRS of the 90th day after onset in the HBOT group was lower than the control group (P =0.003). The multivariate Logistic regression analysis showed that the risk factor associated with treatment effect in the HBOT group was frequency of HBOT (OR 0.790, 95%CI 0.681-0.903, P =0.001). Conclusion HBOT is effective and safe after Moyamoya disease. Frequency of HBOT is the factor to influence on the treatment effect.

Clinical Characteristics and Outcome of Benign Paroxysmal Positional Vertigo

LYU Xiao-Yu,JU Yi, ZHAO Xing-Quan

2016, 11(12):  1023-1029.  DOI: 10.3969/j.issn.1673-5765.2016.12.006

Asbtract ( )   PDF (2375KB) ( )  

References | Related Articles | Metrics

Objective To investigate the clinical characteristics and outcome of benign paroxysmal positional vertigo (BPPV). Methods A total of 1046 cases of BPPV who were diagnosed with BPPV and got cured by canalith repositioning maneuver (CRM) in the Beijing Tiantan Hospital of Capital Medical University from July 2009 to June 2015 were enrolled. All the patients were followed up since December 2015, with the aim of determining the outcomes. All data were analyzed and compared by using SPSS 22.0. Results ①The prevalence of BPPV increased among women, with peak onset between 50 and 60 years of age and a female-to-male ratio of 2:1. ②The recurrence rate of BPPV was 27.20%. According to Logistic regression multivariate analysis, recurrences were seen significantly more often in patients with Meniere's disease (15.567 times, P <0.001), migraines (3.003 times, P <0.01), hypertension (1.554 times, P <0.05) and hyperlipidemia (1.457 times, P <0.05). Conclusion BPPV is commonly seen in mid-aged patients with women higher than men. PSCBPPV was the majority. Meniere's disease, migraines, hypertension and hyperlipidemia might be the risk factors for BPPV recurrence.

Study on Magnetic Resonance Imaging-Arterial Spin Label-Guided Intravenous Thrombolysis in Acute Ischemic Stroke

XU Dong, ZHAO Hai-Yan, MA Dong-Ming, et al.

2016, 11(12):  1030-1034.  DOI: 10.3969/j.issn.1673-5765.2016.12.007

Asbtract ( )   PDF (2515KB) ( )  

References | Related Articles | Metrics

Objective To evaluate the effectiveness and safety of magnetic resonance imaging (MRI)-arterial spin label (ASL) guided intravenous thrombolysis in treatment of acute ischemic stroke (AIS), and to explore a new efficient method of evaluating the intravenous thrombolysis of AIS. Methods Patients with AIS who were treated with recombinant tissue plasminogen activator (rt-PA) guided by MRI-ASL after 3 hours of symptom onset were enrolled as study group, and patients who were treated with rt-PA guided by MRI-perfusion-weighted imaging (PWI) were chosen as control group. The baseline information, medical history, image to needle time (INT), National Institutes of Health Stroke Scale (NIHSS) and modified Rankin's Score (mRS) within 90 d after treatment, the risk of hemorrhagic complications were assessed. Results There were neither significant differences between two groups in the rate of hemorrhagic transformation, nor in the baseline. INT of ASL-group was significantly shorter than that of PWIgroup [(65±15) min vs (73±11) min, P =0.031]. Conclusion Compared with MRI-PWI guided intravenous thrombolysis in treatment of AIS, MRIASL reduces time delay, and there was no significant differences in the safety and effectiveness.

Curcumin Protects Rat Brains Against Cerebral Ischemia by Down-regulating the Expression of Notch 1 and NF-κB

LI Shu-Ya, WANG Yi-Long, WANG Chun-Xue, et al.

2016, 11(12):  1035-1039.  DOI: 10.3969/j.issn.1673-5765.2016.12.008

Asbtract ( )   PDF (2574KB) ( )  

References | Related Articles | Metrics

Objective To investigate the relationship between CUR and the expression of Notch 1 and NF-κB, and evaluate the neuroprotection of CUR in rat permanent middle cerebral artery occlusion (MCAO). Methods A total of ninety-three male, Sprague-Dawley rats were subjected to MCAO. Among which, sixty-three rats were used to investigate the relationship between CUR and the expression of Notch 1 and NF-κB after cerebral ischemia, and 30 rats were used to detect the effect of CUR in the acute phase of ischemic stroke. Neurological deficit, brain water content and infarct sizes were measured at 48 h after MCAO. Immunohistochemistry and Western blot were used to analyze the expression of Notch 1 and NF-κB. Results Compared with sham group, the expression of Notch 1 was up-regulated at early stage after cerebral ischemia. CUR down-regulated the expression of Notch 1 and NF-κB, and the inhibition effect lasted at least 72 hours after MCAO (P <0.05). Compared with vehicle-control group, CUR dramatically improved neurological deficit at 48 h (P <0.05), reduced brain water content [(80.42±9.00)% vs (83.71±7.00)% (P <0.05)] and infarct volume [(40.08±3.66)% vs (28.94±6.20)% (P <0.05)].Conclusion CUR protects the brain from damage caused by cerebral ischemia; this effect may be through down-regulating the expression of Notch 1 and NF-κB.

Traditional Chinese Medicine Serves as a Predecessor in Treatment of Stroke — a Brief Overview of History

John H.Zhang

2016, 11(12):  1042-1044.  DOI: 10.3969/j.issn.1673-5765.2016.11.009

Asbtract ( )   PDF (2001KB) ( )  

Related Articles | Metrics

Progress of Imaging Study on Urination Dysfunction after Stroke

WANG Ru-Jia, SHEN Gui-Quan, GAO Bo

2016, 11(12):  1046-1050.  DOI: 10.3969/j.issn.1673-5765.2016.12.010

Asbtract ( )   PDF (2119KB) ( )  

References | Related Articles | Metrics

Urination dysfunction is one of the most common complications after stroke, which seriously affect the quality of patients' life. The imaging findings of urination dysfunction are summarized in this paper. By learning the imaging features, we would have a more profound understanding of urination disorder after stroke.

A Case Report on Recurrent Urine Retention after Stroke

WANG Xiao-Li, WEI Xiang-Yang,QU Yang, et al.

2016, 11(12):  1051-1053.  DOI: 10.3969/j.issn.1673-5765.2016.12.011

Asbtract ( )   PDF (1818KB) ( )  

References | Related Articles | Metrics

A Case Report on Endovascular Treatment of Carotid Artery Initial Segment Stenosis with Concomitant Unilateral Traffic Segment Ruptured Aneurysm

LI Zhi-Wei, LYU Hua, LIU Jun,et al.

2016, 11(12):  1054-1056.  DOI: 10.3969/j.issn.1673-5765.2016.12.012

Asbtract ( )   PDF (1859KB) ( )  

References | Related Articles | Metrics

Expert Consensus on Diagnosis and Treatment of Neurogenic Bladder after Stroke Chinese Geriatrics Society of Neurology, Stroke Association of Tianjin

Byliner: WANG Yi, ZHAO Yao-Rui

2016, 11(12):  1057-1066.  DOI: 10.3969/j.issn.1673-5765.2016.12.013

Asbtract ( )   PDF (2333KB) ( )  

References | Related Articles | Metrics

Application Research Progress about Glycosylated Hemoglobin A1c in Patients with Ischemic Stroke

LIU Li-Li, LI Guo-Zhong, ZHONG Di, et al.

2016, 11(12):  1067-1071.  DOI: 10.3969/j.issn.1673-5765.2016.12.014

Asbtract ( )   PDF (2045KB) ( )  

References | Related Articles | Metrics

Glycosylated hemoglobin A1c (HbA1c) is an accurate and stable parameter that reflects glycemic level in human body of certain time. It participates in the progress of ischemic stroke and influences the prognosis of patients. So HbA1c could be taken as a routine monitoring index for ischemic stroke and to guide the treatment and prognosis. This article will introduce the present situation of the HbA1c in the development, diagnosis, treatment and prognosis of the patients with ischemic stroke.

Study Progress of Stroke Assessment Scale

WANG Yun-Xiao, YUAN Jun-Liang, HU Wen-Li

2016, 11(12):  1072-1077.  DOI: 10.3969/j.issn.1673-5765.2016.12.015

Asbtract ( )   PDF (2032KB) ( )  

References | Related Articles | Metrics

Stroke is a cerebrovascular disease with high incidence, high mortality rate and high lethal rate, and it is the first leading cause for death in China. The assessment scales in stroke are commonly used in clinical diagnosis and treatment as well as evaluation system for clinical research, such as Glasgow Coma Scale, National Institutes of Health Stroke Scale, Barthel index, and modified Rankin Scale. Our review mainly focuses on the limitations and clinical applications of these scales, so as to better provide guidance for clinical application and scientific research for the stroke scale.

Study Progress of Blood Plasma Biomarker of Ischemic Stroke in Different Subtypes

WANG Yuan, PAN Xu-Dong

2016, 11(12):  1078-1085.  DOI: 10.3969/j.issn.1673-5765.2016.12.016

Asbtract ( )   PDF (2075KB) ( )  

References | Related Articles | Metrics

Ischemic stroke is divided into large artery atherosclerotic cerebral infarction (LAA), small artery occlusion type stroke (SAO), cardiac embolism (CE), stroke of other determined etiology (SOE) and stroke of undetermined etiology (SUE) according to the type Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. The aetiological agent of ischemic stroke is complicated. But there are still some patients who can not be made an accurate classification of subtypes even though the cerebral imaging examination and cardiac examination are perfectly in clinical practice. In recent years, the detection of blood plasma biomarker related with stroke is increasing. This article reviews the progress of study on the blood plasma biomarkers in different subtypes of ischemic stroke. In this review, we aim to explore the change of plasma biomarkers in different subtypes of stroke and its value of clinical application.

Discussion about Teaching Method of Establishment of the Effective Mode of Clinical Thinking on Junior Neuro-intensive Physician

ZHAO Jing-Wei, WANG Qiang

2016, 11(12):  1086-1088.  DOI: 10.3969/j.issn.1673-5765.2016.12.017

Asbtract ( )   PDF (1783KB) ( )  

References | Related Articles | Metrics

As an emerging subspecialty, the theoretical system of neuro-critical care is incomplete. The main study subjects include severe cerebral vascular diseases, craniocerebral trauma, cerebral tumor and other neuro-system related critical patients. Consequently, there are numerous inconsistent conclusions among different studies. In view of this, the authors analyzed the fundamental conceptions of Evidence Based Medicine (EBM) based on traditional philosophy and introduced the conception of evidence chain. Hopefully, this paper will help the junior neurointensive physicians to better understand those complex evidences from EBM, and assist them in the establishment of the effective mode of clinical thinking.

Application of Multiple Teaching Methods in Standardization Training of Residential Physicians of Department of Neurology

WANG Yi, XING Yu-Xi

2016, 11(12):  1089-1091.  DOI: 10.3969/j.issn.1673-5765.2016.12.018

Asbtract ( )   PDF (1822KB) ( )  

References | Related Articles | Metrics

In allusion to the problems of non-standardized physical examination of the nervous system, insufficient diagnostic methods and clinical skill training, inappropriate management and training within the Department of Neurology, the paper is to raise the solution to improve the training system and methods through introducing multiple methods, so that the clinical teacher could fulfill the goal of standardization training of high quality within a limited time.