Clinical Analysis of Cancer Patients Complicated by Pulmonary Embolism to Start with Syncope
WANG Ji-Yun
2011, 6(08):
627-631.
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Objective To analyse the clinical charateristics of cancers complicated by pulmonary embolism in order to detect pulmonary embolism early and start therapy early.Methods We enrolled 11 inpatient and outpatient department patients aged 31-85years old continuously from March, 2006 to January, 2011. All patients are diagnosed with cancers. All cancers are confirmed by pathological examination, lab tests, physical checkup and clinical presentations. Eight cases are diagnosed with pulmonary embolism by pulmonary ventilation/perfusion imaging, 3 cases are diagnosed by spiral computed tomographic pulmonary angiography. We analysed the contributed cancer etiology and their related clinical presentation.Results Mean age is 63±17 years old. Eight cases are male(81.8%), three cases are female(27.3%). Gastric cancer(27.3%), prostate cancer(18.2%), breast cancer(9.1%), ovarian cancer(18.2%), colon cancer(9.1%), pulmonary cancer(18.2%) are the most frequently seen cancers complicated by pulmoary embolism. Related clinical presentations are syncope(27.3%), orthostatic hypotension(27.3%), sinus tachycardia(18.2%), dyspnea(63.6%), chest pain(36.4%), leg and ankle edema(9.1%), anxiety and tension emotion(9.1%). All patients are anticoagulated fully by low molecular weight heparin and oral warfarin. Symptom disappeared and no patients died during the study.Conclusion Cancer is a very important risk factor for pulmonary embolism, especially the cancer types found in this study. Be aware of the symptoms found in the study in order to screen pulmonary embolism.【Key Words】 Neoplasms; Pulmonary embolism; Syncope; Hypotension, orthostatic