Objective To investigate risk factors for hemodynamic depression in perioperative period of
carotid angioplasty and stenting (CAS).
Methods A total of 86 patients who underwent CAS were enrolled. According to the patients’
intraoperative and postoperative blood pressure and heart rate, the patients were divided into no
hemodynamic depression and hemodynamic depression groups. Univariate analysis was used to
find the risk factors of hemodynamic depression, then the logistic regression analysis was used to
determine the dependent risk factors after adjusting for age and sex.
Results Among all 86 patients, 42 (48.8%) had hemodynamic depression of hypotension and
bradycardia. Univariate analysis showed that hemodynamic depression was associated with the age
≥75 years (χ 2=4.076, P =0.040), severe internal carotid stenosis (70%-99%) (χ 2=5.010, P =0.029),
calcified plaque (χ 2=4.432, P =0.035), the distance from stenosis to bifurcation ≤10 mm (χ 2=9.704,
P =0.002), post-balloon dilatation (χ 2=6.635, P =0.025). Multivariate logistic regression analysis
showed that the distance from stenosis to bifurcation ≤10 mm [odds ratio (OR) 2.487, 95% confidence
interval (CI) 1.129-3.479, P =0.021], severe internal carotid stenosis (OR 1.650, 95%CI 1.142-4.156,
P =0.035), post-balloon dilatation (OR 2.628, 95%CI 1.763-4.508, P =0.019) were independent risk
factors of hemodynamic depression.
Conclusions Hemodynamic depression is a common complication in perioperative period of CAS.
The distance from stenosis to bifurcation ≤ 10 mm, severe internal carotid stenosis (70%-99%), and
post-balloon dilatation are independent risk factors of hemodynamic depression related with CAS.
