关键词: 运动神经元病; 肌萎缩侧索硬化; 医疗质量; 质量控制

Abstract: Motor neuron disease (MND) is a group of neurodegenerative diseases, with amyotrophic lateral sclerosis (ALS) being the primary type of MND. At present, ALS/MND lacks specific diagnosis and treatment methods, and the prognosis of patients is poor. Although ALS/MND is rare, there is a rapid increase in the number of hospitalized patients in China. Considering the practical situation in China, there is an urgent need for standardized medical quality control system of ALS/MND. The National Center for Healthcare Quality Management in Neurological Diseases set up the MND Working Group in 2022 and initiated the construction of a clinical quality control system for ALS/MND. Through systematic research, the MND Working Group formulated the core concept of “establishing a medical standard and continuous quality improvement system for MND in China” and utilized the Delphi method to develop quality control indicators in ALS. This includes systematic quality control of the inpatient diagnosis and treatment process of ALS, covering unified diagnostic standards, a comprehensive patient management approach, and standardized treatment protocols. Beyond quality control indicators, the working group also carried out the work of promoting the core data elements of clinical diagnosis and treatment, the construction of the MND quality control information platform, and ensuring the consistency of clinical practice through a national series of standardized teaching sessions. The quality control program should be dynamic, and the working group will integrate practical considerations to ensure the effectiveness and feasibility of the quality control measures in real-world applications. In the future, the continuous development and refinement of this system will provide a scientific and standardized quality control system for the clinical diagnosis and treatment of ALS/MND.

Key words: Motor neuron disease; Amyotrophic lateral sclerosis; Medical quality; Quality control