关键词: 椎底动脉供血不足; 超声检查; 经颅彩色多普勒超声; 脑血管造影术

Abstract: Objective To explore the clinical value of contrast-enhanced transcranial color-codedsonography(CE-TCCS) in diagnosing intracranial vertebro-basilar stenosis and occlusion.Methods Transcranial color-coded sonography(TCCS) was performed in 14 patients who werefirstly diagnosed with stenosis and occlusion of vertebro-basilar artery(VBA) before and afterinjection of ultrasound contrast agent. These two methods were compared with digital subtractionangiography in the diagnosis of VBA stenosis and showed the degree of coincidence.Results A total of 14 patients ,who were suspected to have VBA stenosis including 42 arteries(28vertebro arteries and 14 basilar arteries). The CE-TCCS showed 29 arteries stenosis or occlusionand DSA showed 28 arteries stenosis or occlusion finally. The CE-TCCS showed 13 normal VBAand 12 of them were confirmed by DSA. The TCCS showed 21 arteries stenosis or occlusion andDSA showed 19 arteries stenosis or occlusion finally. The TCCS showed 21 normal VBA andonly 11 of them were confirmed by DSA.The measure of agreement Kappa between TCCS andangiography was 0.429, P <0.05. Meanwhile, the measure of agreement Kappa between CE-TCCSand angiography was 0.889(P <0.01).Conclusion Contrast-enhanced transcranial color-coded sonography greatly improved the signalsof blood flow in the diagnosis of vertebrobasilar artery stenosis and showed higher consistencywith the results of angiography compared to that of TCCS.

Key words: Vertebrobasilar insufficiency; Ultrasonography; Ultrasonography; Doppler; Transcranial; Cerebral angiography