无症状大脑中动脉闭塞的临床研究

doi:10.3969/j.issn.1673-5765.2021.08.012

摘要/Abstract

摘要： 目的探讨无症状大脑中动脉闭塞患者的临床和影像学特点。方法回顾性分析2016年1月-2019年1月连续住院并行头颅MRA检查患者的临床及影像学资料，选择无症状性大脑中动脉主干闭塞患者作为研究对象，分析其临床和影像学特点。结果研究共筛查3967例行头颅MRA检查的患者，其中无症状大脑中动脉闭塞者23例（0.58%），年龄34～80岁，平均61.2±11.2岁；男性14例（60.87%），女性9例（39.13%）；既往高血压14例（60.87%）、高脂血症12例（52.17%）、脑梗死病史6例（26.09%）、高同型半胱氨酸血症8例（34.78%）、糖尿病6例（26.09%）、吸烟4例（17.39%）。头颅MRA检查显示左侧大脑中动脉闭塞10例（43.48%），右侧大脑中动脉闭塞10例（43.48%），双侧大脑中动脉均闭塞3例（13.04%）。随访3个月～3年，患者均无新发脑梗死症状。结论大脑中动脉闭塞可以无相应临床症状和脑梗死病灶而孤立存在，是一种值得进一步研究的脑血管病状态。

文章导读： 本研究通过对3967例住院患者的头颅MRA检查结果进行回顾，发现无症状性大脑中动脉闭塞的检出率为0.58%，患者多数存在血管危险因素，多为单侧血管闭塞，随访期间此类患者均未发生闭塞血管供血区的梗死。

关键词: 无症状性闭塞; 大脑中动脉; 磁共振成像; 脑梗死

Abstract: Objective To analyze the clinical and imaging features of the patients with asymptomatic middle cerebral artery (MCA) occlusion. Methods A retrospective analysis of the data of inpatients with asymptomatic MCA occlusion who underwent head MRA from January 2016 to January 2019 was performed, to analyze the clinical and imaging features of all the included patients. Results Totals of 3967 patients underwent head MRA examination, and among them, 23 cases (0.58%) with asymptomatic MCA occlusion. For the 23 subjects, the mean age was 61.2±11.2 years (range: 34-80 years), and 14 were male (60.87%) and 9 were female (39.13%). Among them, there were 14 cases with a history of hypertension (60.87%), 12 with hyperlipidemia (52.17%), 6 with a history of stroke (26.09%), 8 with hyperhomocysteinemia (34.78%), 6 with diabetes (26.09%) and 4 with a history of smoking (17.39%). MRA imaging showed 10 cases (43.48%) with left MCA occlusion, 10 cases (43.48%) with right MCA occlusion and 3 cases (13.04%) with bilateral MCA occlusion. During the follow-up of 3 months to 3 years, none had symptoms of new cerebral infarction. Conclusions MCA occlusion can exist in isolation without corresponding clinical symptoms and cerebral infarction lesions, which is worthy of further study.

Key words: Asymptomatic occlusion; Middle cerebral artery; Magnetic resonance imaging;Cerebral infarction

李如娟, 马晓丹, 杨川, 马晓辉, 杨金波. 无症状大脑中动脉闭塞的临床研究[J]. 中国卒中杂志, 2021, 16(08): 822-827.

LI Ru-Juan, MA Xiao-Dan, YANG Chuan, MA Xiao-Hui, YANG Jin-Bo. Clinical Study of Asymptomatic Middle Cerebral Artery Occlusion[J]. Chinese Journal of Stroke, 2021, 16(08): 822-827.

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