关键词: 颅内动脉狭窄; 支架; 血管成形术; 认知功能

Abstract: Objective To analyze the preliminary short-term outcome, especially the effect on cognitivefunction, and the safety of stenting for intracranial artery stenosis.Methods Patients with intracranial artery stenting were monitored by transcranial Dopplersonography(TCD), mini-mental state examination(MMSE) and P300 before and 1, 3 and 6 monthsafter stenting.Results Total 52 patients with atherosclerotic intracranial artery stenosis were enrolled in our study.24 stenosis in M1 segment of middle cerebral artery and 28 in intracranial vertebral artery. Technicalsuccess was achieved in all patients, with no procedure-associated complications. The residualstenosis(7%±5%) after stenting reduced significantly compared with pre-procedure stenosis(78％±10%). At 1, 3 and 6 months after stenting, the scores of MMSE were significantly higher and thelatent phase of P300 were shortened significantly (P <0.01), especially at 6 months. The patients hadno recurrent transient ischemia attach or stroke, and TCD revealed no restenosis during 6 monthsfollow-up.Conclusion Stenting of intracranial artery stenosis may be safe, feasible and favorable fordecreasing ischemic events and improving cognitive function during short-term follow-up. But theeffect of long-term will be studied further.

Key words: Intracranial artery stenosis; Stenting; Angioplasty; Cognitive function