Abstract:

Objective To probe into the endovascular stent angioplasty in the treatment of symptomatic middle cerebral artery stenosis, and evaluate its safety and therapeutic effect. Methods A retrospective analysis of the patients with middle cerebral artery stenosis who had received endovascular stent angioplasty treatment from May 2008 to December 2015 in Neurology Department, Cangzhou City People's Hospital was made to observe the success rate of endovascular stent, surgical complication rate, preoperative and postoperative stenosis stent rate, and follow-up the therapeutic effect of patients who had endovascular stent angioplasty. Results A total of 98 patients who have been successfully implanted brackets were enrolled into the group. The preoperative stenosis rate was (83.8±7.9)% on average, and postoperative residual stenosis rate was (21.9±4.2)%. There was 1 case (1.0%) of subacute thrombus which happened 3 days after the operation, with the restenosis rate of 12.9%. The 1 year follow-up cumulative incidence of endpoint events (onset of ischemic stroke at 30 d after operation, hemorrhagic stroke and operation associated death, ischemic stroke within the lesion region after 30 d) was 14.3%. Conclusion Endovascular stent angioplasty shows good therapeutic effect and safety, high success rate of the operation, and low incidence of 1 year restenosis.

Key words: 【Key Words】 Middle cerebral artery; Endovascular angioplasty; Stenting; Stenosis rate; End point events

摘要：

目的 探讨血管内支架成形术在症状性大脑中动脉血管狭窄治疗中的应用，评价其安全性及治疗 效果。 方法 回顾性分析2008年5月-2015年2月在沧州市人民医院神经内科行血管内支架成形术治疗的症 状性大脑中动脉狭窄患者，观察血管内支架置入成功率、手术并发症、支架术前后血管狭窄率并随访 血管内支架成形术的治疗效果。 结果 入组98例患者，均成功置入支架，术前患者平均狭窄率为（83.8±7.9）%，术后患者残余狭窄 率为（21.9±4.2）%，术后3 d发生亚急性血栓1例（1.0%），再狭窄发生率12.9%（10/77），随访1年疗 效终点事件（术后30 d内发生缺血性卒中、出血性卒中及手术相关性死亡；30 d后发生病变血管责任区 域内的缺血性卒中）累计发生率为14.3%（14/98）。 结论 血管内支架成形术治疗症状性大脑中动脉狭窄具有良好的安全性，手术成功率高，1年再狭窄 率低。

关键词: 大脑中动脉; 血管成形术; 支架; 狭窄率; 终点事件