Advance in Research of the Relationship between Mild Cognitive Impairment and Post-stroke Depression

doi:10.3969/j.issn.1673-5765.2018.06.020

Abstract

Abstract:

Mild cognitive impairment (MCI) is a transition state between normal cognition and dementia. MCI has a close relationship with Post-stroke depression (PSD). MCI with depression is common. PSD is also considered to be an important risk factor for MCI progressing to dementia. The research progress of the relations between PSD and MCI is reviewed in the paper, which is emphatically recommends the new progress in MCI and PSD, including epidemiology, related mechanisms, and treatment.

Key words: Mild cognitive impairment; Depression; Post-stroke depression

摘要：

轻度认知障碍（mild cognitive impairment，MCI）是认知正常和痴呆之间的过渡状态，MCI与卒中后抑郁（post-stroke depression，PSD）关系密切。MCI常伴发抑郁，而PSD亦被认为是MCI向痴呆进展的重要危险因素。本文就MCI与PSD关系的研究进展进行综述，着重介绍MCI和PSD关系的新进展，包括流行病学、相关机制及治疗。

关键词: 轻度认知障碍; 抑郁; 卒中后抑郁

LI Shi-Wen, QIU Xiao-Xue, WU Yi-Ping, LIN Jie. Advance in Research of the Relationship between Mild Cognitive Impairment and Post-stroke Depression[J]. Chinese Journal of Stroke, 2018, 13(06): 631-635.

李世文, 邱晓雪, 武一平, 林杰. 轻度认知障碍与卒中后抑郁关系的研究进展[J]. 中国卒中杂志, 2018, 13(06): 631-635.

References

[1] PETERSEN R C，SMITH G E，WARING S C，et al.

Mild cognitive impairment：clinical characterization

and outcome[J]. Arch Neurol，1999，56（3）：303-308.

[2] MAKIZAKO H，SHIMADA H，DOI T，et al.

Comorbid Mild cognitive impairment and depressive

symptoms predict future dementia in community

older adults：a 24-month follow-up longitudinal

study[J]. J Alzheimers Dis，2016，54（4）：1473-1482.

[3] KIDA J，NEMOTO K，IKEJIMA C，et al. Impact

of depressive symptoms on conversion from mild

cognitive impairment subtypes to Alzheimer's

disease：a community-based longitudinal study[J]. J

Alzheimers Dis，2016，51（2）：405-415.

[4] GABRYELEWICZ T，STYCZYNSKA M，

LUCZYWEK E，et al. The rate of conversion of mild

cognitive impairment to dementia：predictive role of

depression[J]. Int J Geriatr Psychiatry，2007，22（6）：

563-567.

[5] PETERSEN R C，LOPEZ O，ARMSTRONG M

J，et al. Practice guideline update summary：Mild

cognitive impairment：Report of the Guideline

Development，Dissemination，and Implementation

Subcommittee of the American Academy of

Neurology[J]. Neurology，2018，90（3）：126-135.

[6] 王少石，周新雨，朱春燕. 卒中后抑郁临床实践的中

国专家共识[J]. 中国卒中杂志，2016，11（8）：685-

693.

[7] LANGA K M，LEVINE D A. The diagnosis and

management of mild cognitive impairment：a clinical

review[J]. JAMA，2014，312（23）：2551-2561.

[8] ZAKHAROV VV，GROMOVA DO. Current

approaches to management of patients with mild

cognitive impairment[J]. Zh Nevrol Psikhiatr Im S S

Korsakova，2017，117（3）：107-112.

[9] WADSWORTH L P，LORIUS N，DONOVAN N

J，et al. Neuropsychiatric symptoms and global

functional impairment along the Alzheimer's

continuum[J]. Dement Geriatr Cogn Disord，2012，

34（2）：96-111.

[10] JIA J，ZHOU A，WEI C，et al. The prevalence

of mild cognitive impairment and its etiological

subtypes in elderly Chinese[J]. Alzheimers Dement，

2014，10（4）：439-447.

[11] WEI C，ZHANG F，CHEN L，et al. Factors

associated with post-stroke depression and fatigue：

lesion location and coping styles[J]. J Neurol，2016，

263（2）：269-276.

[12] SCH.TTKE H，GIABBICONI C M. Post-stroke

depression and post-stroke anxiety：prevalence

and predictors[J]. Int Psychogeriatr，2015，27（11）：1805-1812.

[13] TERRONI L，SOBREIRO M F M，CONFORTO A

B，et al. Association among depression，cognitive

impairment and executive dysfunction after stroke[J].

Dement Neuropsychol，2012，6（3）：152-157.

[14] TEETERS D A，MOUA T，LI G，et al. Mild

cognitive impairment and risk of critical illness[J].

Crit Care Med，2016，44（11）：2045-2051.

[15] GIULI C，FABBIETTI P，PAOLONI C，et al.

Subjective memory complaints in Italian elderly

with mild cognitive impairment：implication of

psychological status[J]. Neurol Sci，2016，37（7）：

1153-1157.

[16] HIDAKA S，IKEJIMA C，KODAMA C，et al.

Prevalence of depression and depressive symptoms

among older Japanese people：comorbidity of mild

cognitive impairment and depression[J]. Int J Geriatr

Psychiatry，2012，27（3）：271-279.

[17] IHLE-HANSEN H，THOMMESSEN B，WYLLER T

B，et al. Incidence and subtypes of MCI and dementia

1 year after first-ever stroke in patients without preexisting

cognitive impairment[J]. Dement Geriatr

Cogn Disord，2011，32（6）：401-407.

[18] ZHAO W，JIANG F，ZHANG Z，et al. Remote

ischemic conditioning：a novel non-invasive

approach to prevent post-stroke depression[J/OL].

Front Aging Neurosci，2017，9：270. https：//doi.

org/10. 3389/fnagi. 2017. 00270.

[19] BARNES D E，YAFFE K. The projected effect of risk

factor reduction on Alzheimer's disease prevalence[J].

Lancet Neurol，2011，10（9）：819-828.

[20] 刘静波. 脑卒中后患者抑郁与认知损害的交互影响

研究[J]. 重庆医学，2015，44（1）：113-115.

[21] 王娟. 认知护理干预对脑卒中后抑郁症患者神经

和认知功能的影响分析[J]. 世界最新医学信息文摘，

2017，8（23）：143-144.

[22] SWARTZ R H，BAYLEY M，LANCT.T K L，et al.

Post-stroke depression，obstructive sleep apnea，and

cognitive impairment：Rationale for，and barriers to，

routine screening[J]. Int J Stroke，2016，11（5）：509-

518.

[23] STEPHAN B C，MINETT T，TERRERA G M，et

al. Dementia prediction for people with stroke in

populations：is mild cognitive impairment a useful

concept?[J]. Age Ageing，2015，44（1）：78-83.

[24] PALMER S M，CREWTHER S G，CAREY L M，

et al. A meta-analysis of changes in brain activity

in clinical depression[J/OL]. Front Hum Neurosci，

2015，8：1045. https：//doi. org/10. 3389/fnhum. 2014.

01045.

[25] MOURAO R J，MANSUR G，MALLOY-DINIZ

L F，et al. Depressive symptoms increase the risk

of progression to dementia in subjects with mild

cognitive impairment：systematic review and metaanalysis[

J]. Int J Geriatr Psychiatry，2016，31（8）：

905-911.

[26] ZHANG Z H，WU L N，SONG J G，et al.

Correlations between cognitive impairment and

brainderived neurotrophic factor expression in the

hippocampus of post-stroke depression rats[J]. Mol

Med Rep，2012，6（4）：889-893.

[27] 史宇，杨冬冬，黄国志，等. 卒中后抑郁发病机制及相

关影响因素[J]. 实用医学杂志，2016（06）：867-869.

[28] KOEN J D，YONELINAS A P. The effects of healthy

aging，amnestic mild cognitive impairment，and

Alzheimer's disease on recollection and familiarity：

a meta-analytic review[J]. Neuropsychology Rev，

2014，24（3）：332-354.

[29] JOKO T，WASHIZUKA S，SASAYAMA D，et

al. Patterns of hippocampal atrophy differ

among Alzheimer's disease，amnestic mild

cognitive impairment，and late-life depression[J].

Psychogeriatrics，2016，16（6）：355-361.

[30] ARAUZ A，RODRIGUEZ-AGUDELO Y，SOSA A

L，et al. Vascular cognitive disorders and depression

after first-ever stroke：the Fogarty-Mexico Stroke

Cohort[J]. Cerebrovasc Dis，2014，38（4）：284-289

[31] 董强，郭起浩，罗本燕，等. 卒中后认知障碍管理专

家共识[J]. 中国卒中杂志，2017，12（6）：519-531.

[32] K WARD S，TURNER A，A HAMBRIDGE J，et

al. Group cognitive behavioural therapy for stroke

survivors with depression and their carers[J]. Top

Stroke Rehabil，2016，23（5）：358-365.

[33] VEMURI P，LESNICK T G，PRZYBELSKI S A，et

al. Association of lifetime intellectual enrichment

with cognitive decline in the older population[J].

JAMA Neurol，2014，71（8）：1017-1024.