HAO Rui-Xiao, WU Jia-Ling. Progress of High Density Lipoprotein Cholesterol Level and Small Artery Occlusion Stroke[J]. Chinese Journal of Stroke, 2019, 14(09): 902-908.
[1] ABDULRAHIM A H,FULTON R L,SUCHAREWH,et al. National institutes of health stroke scaleitem profiles as predictor of patient outcome:external validation on independent trial data[J].Stroke,2015,46(2):395-400.[2] ADAMS H P Jr,BENDIXEN B H,KAPPELLE LJ,et al. Classification of subtype of acute ischemicstroke. Definitions for use in a multicenter clinicaltrial. TOAST. Trial of Org 10172 in Acute StrokeTreatment[J]. Stroke,1993,24(1):35-41.[3] BAMFORD J,SANDERCOCK P,JONES L,etal. The natural history of lacunar infarction:theOxfordshire Community Stroke Project[J]. Stroke,1987,18(3):545-551.[4] Lavallée P C,Labreuche J,Faille D,et al.Circulating markers of endothelial dysfunctionand platelet activation in patients with severesymptomatic cerebral small vessel disease[J].Cerebrovasc Dis,2013,36(2):131-138.[5] KOLOMINSKY-RABAS P L,WEBER M,GEFELLER O,et al. Epidemiology of ischemicstroke subtypes according to TOAST criteria:incidence,recurrence,and long-term survivalin ischemic stroke subtypes:a population-basedstudy[J]. Stroke,2001,32(12):2735-2740.[6] WANG J,BIE J,GHOSH S. Intracellular cholesteroltransport proteins enhance hydrolysis of HDL-CEsand facilitate elimination of cholesterol into bile[J]. JLipid Res,2016,57(9):1712-1719.[7] MARQUES L R,DINIZ T A,ANTUNES BM,et al. Reverse cholesterol transport:molecularmechanisms and the non-medical approach toenhance HDL cholesterol[J/OL]. Front Physiol,2018,9:526. https://doi.org/10.3389/fphys.2018.00526.[8] PÉREZ-MÉNDEZ Ó,PACHECO H G,MARTÍNEZ-SÁNCHEZ C,et al. HDL-cholesterolin coronary artery disease risk:function orstructure?[J/OL]. Clin Chim Acta,2014,429:111-122. https://doi.org/10.1016/j.cca.2013.12.001.[9] Pullicino P M. Pathogenesis of lacunar infarcts andsmall deep infarcts[J]. Adv Neurol,1993,62:125-140.[10] RADER D J,ALEXANDER E T,WEIBEL GL,et al. The role of reverse cholesterol transportin animals and humans and relationship toatherosclerosis[J]. J Lipid Res,2009,50(Suppl):S189-S194.[11] ROSENSON R S,BREWER H B Jr,DAVIDSONW S,et al. Cholesterol efflux and atheroprotection:advancing the concept of reverse cholesteroltransport[J]. Circulation,2012,125(15):1905-1919.[12] NOFER J R. Signal transduction by HDL:agonists,receptors,and signaling cascades[J/OL]. HandbExp Pharmacol,2015,224:229-256. https://doi.org/10.1007/978-3-319-09665-0_6.[13] TRIGATTI B L,FULLER M. HDL signaling andprotection against coronary artery atherosclerosis inmice[J]. J Biomed Res,2016,30(2):94-100.[14] GAO M,ZHAO D,SCHOUTEDEN S,etal. Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells inatherosclerosis requires scavenger receptor type BIexpression[J]. Arterioscler Thromb Vasc Biol,2014,34(9):1900-1909.[15] SAITO I,YAMAGISHI K,KOKUBO Y,et al.Association of high-density lipoprotein cholesterolconcentration with different types of stroke andcoronary heart disease:The Japan Public HealthCenter-based prospective(JPHC)study[J/OL].Atherosclerosis,2017,265:147-154. https://doi.org/10.1016/j.atherosclerosis.2017.08.032.[16] MENG G L,TAN Y,FANG M,et al. Paradoxicalelevation of high density lipoprotein cholesterol inassociation with lacunar-type cerebral infarction[J/OL]. Med Sci Monit,2015,21:1872-1878. https://doi.org/10.12659/MSM.893647.[17] BAKKER S L,DE LEEUW F E,KOUDSTAALP J,et al. Cerebral CO2 reactivity,cholesterol,andhigh-density lipoprotein cholesterol in the elderly[J].Neurology,2000,54(4):987-989.[18] TIRSCHWELL D L,SMITH N L,HECKBERT SR,et al. Association of cholesterol with stroke riskvaries in stroke subtypes and patient subgroups[J].Neurology,2004,63(10):1868-1875.[19] HINDY G,ENGSTRÖM G,LARSSON S C,et al.Role of blood lipids in the development of ischemicstroke and its subtypes:a Mendelian RandomizationStudy[J]. Stroke,2018,49(4):820-827.[20] PIKULA A,BEISER A S,WANG J,et al. Lipid andlipoprotein measurements and the risk of ischemicvascular events:Framingham Study[J]. Neurology,2015,84(5):472-479.[21] TONI D,DI ANGELANTONIO E,DI MASCIOM T,et al. Types of stroke recurrence in patientswith ischemic stroke:a substudy from the PRoFESStrial[J]. Int J Stroke,2014,9(7):873-878.[22] ESTRUCH R,ROS E,SALAS-SALVADÓ J,et al.Primary prevention of cardiovascular disease with aMediterranean diet[J]. N Engl J Med,2013,368(14):1279-1290.[23] CHEN G C,NEELAKANTAN N,MARTÍNCALVON,et al. Adherence to the Mediterraneandiet and risk of stroke and stroke subtypes[J]. Eur JEpidemiol,2019,34(4):337-349.[24] TUTTOLOMONDO A,CASUCCIO A,BUTTÀC,et al. Mediterranean Diet in patients withacute ischemic stroke:relationships betweenMediterranean Diet score,diagnostic subtype,andstroke severity index[J]. Atherosclerosis,2015,243(1):260-267.[25] RONDANELLI M,GIACOSA A,MORAZZONIP,et al. MediterrAsian diet products that couldraise HDL-cholesterol:a systematic review[J/OL].Biomed Res Int,2016,2016:2025687. http://dx.doi.org/10.1155/2016/2025687.[26] MILLAR C L,DUCLOS Q,BLESSO C N. Effectsof dietary flavonoids on reverse cholesterol transport,HDL metabolism,and HDL function[J]. Adv Nutr,2017,8(2):226-239.[27] RUIZ-RAMIE J J,BARBER J L,SARZYNSKI MA. Effects of exercise on HDL functionality[J]. CurrOpin Lipidol,2019,30(1):16-23.[28] RAHMATI-AHMADABAD S,BROOM D R,GHANBARI-NIAKI A,et al. Effects of exercise onreverse cholesterol transport:a systemized narrativereview of animal studies[J/OL]. Life Sci. 2019,224:139-148. https://doi.org/10.1016/j.lfs.2019.03.058.[29] GARELNABI M,MAHINI H,WILSON T.Quercetin intake with exercise modulates lipoproteinmetabolism and reduces atherosclerosis plaqueformation[J/OL]. J Int Soc Sports Nutr,2014,11:22.https://doi.org/10.1186/1550-2783-11-22.[30] PINTO P R,DA SILVA K S,IBORRA R T,etal. Exercise training favorably modulates gene andprotein expression that regulate arterial cholesterolcontent in CETP transgenic mice[J/OL]. FrontPhysiol,2018,9:502. https://doi.org/10.3389/fphys.2018.00502.[31] AMARENCO P,BOGOUSSLAVSKY J,CALLAHAN A 3rd,et al. High-dose atorvastatinafter stroke or transient ischemic attack[J]. N Engl JMed,2006,355(6):549-555.[32] AMARENCO P,LABREUCHE J. Lipidmanagement in the prevention of stroke:reviewand updated meta-analysis of statins for strokeprevention[J]. Lancet Neurol,2009,8(5):453-463.[33] HOSOMI N,NAGAI Y,KOHRIYAMA T,et al.The Japan Statin Treatment Against Recurrent Stroke(J-STARS):a multicenter,randomized,open-label,parallel-group study[J]. EBio Medicine,2015,2(9):1071-1078.[34] CASTILLA-GUERRA L,FERNANDEZMORENOM D C,LEON-JIMENEZ D,et al.Statins in ischemic stroke prevention:what have welearned in the post-SPARCL(The Stroke Preventionby Aggressive Reduction in Cholesterol Levels)decade?[J]. Curr Treat Options Neurol,2019,21(5):22.[35] TENENBAUM A,MOTRO M,FISMAN E Z,etal. Bezafibrate for the secondary prevention ofmyocardial infarction in patients with metabolicsyndrome[J]. Arch Intern Med,2005,165(10):1154-1160.[36] WANG D,LIU B,TAO W,et al. Fibrates forsecondary prevention of cardiovascular diseaseand stroke[J/OL]. Cochrane Database SystRev,2015,2015(10):CD009580. https://doi.org/10.1002/14651858.CD009580.pub2.[37] TAYLOR A J,VILLINES T C,STANEK E J,etal. Extended-release niacin or ezetimibe and carotidintima-media thickness[J]. N Engl J Med,2009,361(22):2113-2122.[38] AIM-HIGH Investigators,BODEN W E,PROBSTFIELD J L,et al. Niacin in patients withlow HDL cholesterol levels receiving intensive statintherapy[J]. N Engl J Med,2011,365(24):2255-2267.[39] HPS2-THRIVE Collaborative Group. HPS2-THRIVE randomized placebo-controlled trial in 25673 high-risk patients of ER niacin/laropiprant:trialdesign,pre-specified muscle and liver outcomes,and reasons for stopping study treatment[J]. EurHeart J,2013,34(17):1279-1291.[40] PROBSTFIELD J L,BODEN W E,ANDERSONT,et al. Cardiovascular outcomes during extendedfollow-up of the AIM-HIGH trial cohort[J]. J ClinLipidol,2018,12(6):1413-1419.[41] BODEN W E,SIDHU M S,TOTH P P. Thetherapeutic role of niacin in dyslipidemiamanagement[J]. J Cardiovasc Pharmacol Ther,2014,19(2):141-158.[42] BARTER P J,CAULFIELD M,ERIKSSON M,etal. Effects of torcetrapib in patients at high risk forcoronary events[J]. N Engl J Med,2007,357(21):2109-2122.[43] SCHWARTZ G G,OLSSON A G,ABT M,et al.Effects of dalcetrapib in patients with a recent acutecoronary syndrome[J]. N Engl J Med,2012,367(22):2089-2099.[44] LINCOFF A M,NICHOLLS S J,RIESMEYER JS,et al. Evacetrapib and cardiovascular outcomesin high-risk vascular disease[J]. N Engl J Med,2017,376(20):1933-1942.[45] HPS3/TIMI55-REVEAL Collaborative Group,BOWMAN L,HOPEWELL J C,et al. Effects ofanacetrapib in patients with atherosclerotic vasculardisease[J]. N Engl J Med,2017,377(13):1217-1227.[46] TALL A R,RADER D J. Trials and tribulations ofCETP inhibitors[J]. Circ Res,2018,122(1):106-112.[47] BOHULA E A,WIVIOTT S D,GIUGLIANO RP,et al. Prevention of stroke with the addition ofEzetimibe to statin therapy in patients with acutecoronary syndrome in IMPROVE-IT(ImprovedReduction of Outcomes:Vytorin EfficacyInternational Trial)[J]. Circulation. 2017,136(25):2440-2450.[48] ADACHI H,NAKANO H,YAMAMOTO K,etal. Ezetimibe ameliorates atherogenic lipids profiles,insulin resistance and hepatocyte growth factor inobese patients with hypercholesterolemia[J]. LipidsHealth Dis,2015,14(1):1.[49] AI C,ZHANG S,HE Q,et al. Comparing thecombination therapy of ezetimibe and atorvastatinwith atorvastatin monotherapy for regulating bloodlipids:a systematic review and meta-analyse[J].Lipids Health Dis,2018,17(1):239.[50] EASTON R,GILLE A,D'ANDREA D,et al. Amultiple ascending dose study of CSL112,aninfused formulation of ApoA-Ⅰ[J]. J Clin Pharmacol,2014,54(3):301-310.[51] TRICOCI,D'ANDREA D M,GURBEL P A,et al.Infusion of reconstituted high-density lipoprotein,CSL112,in patients with atherosclerosis:safety andpharmacokinetic results from a phase 2a randomizedclinical trial[J]. J Am Heart Assoc,2015,4(8):e002171. https://doi.org/10.1161/JAHA.115.002171.[52] MICHAEL GIBSON C,KORJIAN S,TRICOCIP,et al. Safety and Tolerability of CSL112,aReconstituted,Infusible,Plasma-DerivedApolipoprotein A-I,After Acute MyocardialInfarction:The AEGIS-I Trial(ApoA-I EventReducing in Ischemic Syndromes I)[J]. Circulation,2016,134(24):1918-1930.[53] KARALIS I,JUKEMA J W. HDL mimeticsinfusion and regression of atherosclerosis:is itstill considered a valid therapeutic option?[J]. CurrCardiol Rep,2018,20(8):66.