Abstract:

Objective To observe the effect of nursing in hyperbaric oxygen (HBO) in children with ischemic moyamoya disease. Methods This retrospective analysis enrolled the children with ischemic moyamoya disease (aged 1 to 16 years old) who were admitted to Department of Hyperbaric Oxygen of Beijing Tiantan Hospital from September 2012 to August 2019. Based on the date of starting HBO nursing in September 2015, all the patients were divided into control group and nursing group. Good prognosis was defined as a mRS score of 0 to 2. The difference in the percentage of completing HBO treatment ≥5 times, adverse reaction, and the percentage of 90-day good prognosis in children who had completed HBO treatment ≥5 times between the two groups were compared. Results A total of 84 cases were included in this analysis. Nursing group: 48 cases, 25 males, 23 females, the age range of 3 to 16 years, and the mean age of 8.81±3.83 years; control group: 36 cases, 18 males, 18 females, the age range of 2 to 16 years, and the mean age of 9.50±3.60 years. The proportion of patients who completed ≥5 times of HBO treatment in nursing group was higher than that in control group (97.9% vs 83.3%, P =0.02). No patients in both two groups suffered from adverse reaction such as barometric injury, decompression sickness, oxygen toxicity and so on during HBO treatment. 47 cases in nursing group and 30 cases in control group completed ≥5 times of HBO treatment, and they in the two groups had no statistical difference in 90-day good prognosis rate (nursing vs control group: 63.83% vs 60.00%, P =0.60). Conclusions Hyperbaric oxygen nursing can help improve HBO treatment compliance in children with ischemic moyamoya disease, while no improvement in 90-day functional prognosis was observed.

Key words: Ischemic moyamoya disease; Hyperbaric oxygen; Nursing; Adverse reaction

摘要：

目的 观察高压氧护理干预在治疗缺血型烟雾病患儿中的效果。 方法 回顾性纳入首都医科大学附属北京天坛医院高压氧科2012年9月-2019年8月就诊的缺血型烟 雾病患儿（1～16岁）作为观察对象，以2015年9月高压氧护理干预开始实施的时间为节点，分为对照组 （护理干预实施前）和护理组（护理干预实施后），比较两组下列指标的差异：完成治疗≥5次的患儿 比例；不良反应的发生率（气压伤、减压病、氧中毒等）；统计并比较两组中完成5次以上高压氧治疗 患儿发病90 d的预后良好率（mRS评分0～2分）。 结果 研究期间共纳入患儿84例，其中护理组48例，男性25例，女性23例，年龄3～16岁，平均 8.81±3.83岁，对照组36例，男18例，女18例，年龄2～16岁，平均9.50±3.60岁。护理组完成5次及以 上治疗者的比例高于对照组（97.9% vs 83.3%，P =0.02）；两组患儿在高压氧治疗时均未发生气压伤、 减压病及氧中毒等不良反应；护理组完成5次以上高压氧治疗者47例，对照组为30例，这些患儿90 d 预后良好率护理组与对照组差异无统计学意义（63.83% vs 60.00%，P =0.60）。 结论 护理干预能提高缺血型烟雾病患儿高压氧治疗的依从性，但未发现可改善患儿的90 d预后。

关键词: 缺血型烟雾病; 高压氧; 护理; 不良反应