SUN Wei, ZHANG Yu-Sheng. Dilemma in Anticoagulation Field: Stroke Prevention after Anticoagulation-Related Hemorrhage in Patients with Atrial Fibrillation[J]. Chinese Journal of Stroke, 2021, 16(08): 757-761.
[1] 王拥军,李子孝,谷鸿秋,等. 中国卒中报告2019(中
文版)(1)[J]. 中国卒中杂志,2020,15(10):1037-
1043.
[2] 《中国脑卒中防治报告2019》编写组. 《中国脑卒中
防治报告2019》概要[J]. 中国脑血管病杂志,2020,
17(5):272-281.
[3] ZHANG J,YANG X A,ZHANG Y,et al. Oral
anticoagulant use in atrial fibrillation-associated
ischemic stroke:a retrospective,multicenter survey
in northwestern China[J]. J Stroke Cerebrovasc Dis,
2017,26(1):125-131.
[4] LI Y G,LIP G Y H. Stroke prevention in atrial
fibrillation:state of the art[J/OL]. Int J Cardiol,2019,
287:201-209[2021-05-25]. https://doi.org/10.1016/j.
ijcard.2018.09.057.
[5] KURAMATSU J B,HUTTNER H B. Management
of oral anticoagulation after intracerebral
hemorrhage[J]. Int J Stroke Int J Stroke,2019,14(3):
238-246.
[6] HAGERTY T,RICH M W. Fall risk and
anticoagulation for atrial fibrillation in the elderly:a
delicate balance[J]. Cleve Clin J Med,2017,84(1):
35-40.
[7] JANUARY C T,WANN L S,CALKINS H,et al.
2019 AHA/ACC/HRS focused update of the 2014
AHA/ACC/HRS guideline for the management
of patients with atrial fibrillation:a report of the
american college of cardiology/american heart
association task force on clinical practice guidelines
and the heart rhythm society[J]. J Am Coll Cardiol,
2019,74(1):104-132.
[8] STEFFEL J,VERHAMME P,POTPARA T S,et
al. The 2018 European Heart Rhythm Association
practical guide on the use of non-vitamin K
antagonist oral anticoagulants in patients with atrial
fibrillation[J]. Eur Heart J,2018,39(16):1330-
1393.
[9] KIRCHHOF P,BENUSSI S,KOTECHA D,et al.
2016 ESC guidelines for the management of atrial
fibrillation developed in collaboration with eacts[J].
Europace,2016,18(11):1609-1678.
[10] CHANG T Y,LIAO J N,CHAO T F,et al. Oral
anticoagulant use for stroke prevention in atrial
fibrillation patients with difficult scenarios[J/OL]. Int
J Cardiol Heart Vasc,2018,20:56-62[2021-05-25].
https://doi.org/10.1016/j.ijcha.2018.08.003.
[11] LOPES R D,GUIMARAES P O,KOLLS B J,et
al. Intracranial hemorrhage in patients with atrial
fibrillation receiving anticoagulation therapy[J].
Blood,2017,129(22):2980-2987.
[12] TSAI C T,LIAO J N,CHIANG C E,et al.
Association of ischemic stroke,major bleeding,
and other adverse events with warfarin use vs nonvitamin
K antagonist oral anticoagulant use in
patients with atrial fibrillation with a history of
intracranial hemorrhage[J/OL]. JAMA Network
Open,2020,3(6):e206424[2021-05-25].
https://doi.org/10.1001/jamanetworkopen.2020.6424.
[13] PISTERS R,LANE D A,NIEUWLAAT R,et al.
A novel user-friendly score(HAS-BLED)to assess
1-year risk of major bleeding in patients with atrial
fibrillation:the euro heart survey[J]. Chest,2010,
138(5):1093-1100.
[14] LIP G Y,FRISON L,HALPERIN J L,et al.
Comparative validation of a novel risk score
for predicting bleeding risk in anticoagulated
patients with atrial fibrillation:the HAS-BLED
(hypertension,abnormal renal/liver function,stroke,
bleeding history or predisposition,labile inr,elderly,
drugs/alcohol concomitantly)score[J]. J Am Coll
Cardiol,2011,57(2):173-180.
[15] 黄从新,张澍,黄德嘉,等. 心房颤动:目前的认识和
治疗建议(2018)[J]. 中华心律失常学杂志,2018,22
(4):279-346.
[16] O'BRIEN E C,SIMON D N,THOMAS L E,et al.
The orbit bleeding score:a simple bedside score to
assess bleeding risk in atrial fibrillation[J]. Eur Heart
J,2015,36(46):3258-3264.
[17] HIJAZI Z,OLDGREN J,LINDBACK J,et al.
The novel biomarker-based ABC(age,biomarkers,
clinical history)-bleeding risk score for patients
with atrial fibrillation:a derivation and validation
study[J]. Lancet,2016,387(10035):2302-2311.
[18] FANG M C,GO A S,CHANG Y C,et al. A
new risk scheme to predict warfarin-associated
hemorrhage the atria(anticoagulation and risk
factors in atrial fibrillation)study[J]. J Am Coll
Cardiol,2011,58(4):395-401.
[19] BERG D D,RUFF C T,MORROW D A. Biomarkers
for risk assessment in atrial fibrillation[J]. Clin Chem,
2021,67(1):87-95.
[20] WALLENTIN L,HIJAZI Z,ANDERSSON
U,et al. Growth differentiation factor 15,a
marker of oxidative stress and inflammation,for
risk assessment in patients with atrial fibrillation:
insights from the apixaban for reduction in stroke
and other thromboembolic events in atrial fibrillation
(aristotle)trial[J]. Circulation,2014,130(21):
1847-1858.
[21] HAGSTROM E,JAMES S K,BERTILSSON M,et
al. Growth differentiation factor-15 level predicts
major bleeding and cardiovascular events in patients
with acute coronary syndromes:results from the
plato study[J]. Eur Heart J,2016,37(16):1325-
1333.
[22] BERG D D,RUFF C T,JAROLIM P,et al.
Performance of the abc scores for assessing the
risk of stroke or systemic embolism and bleeding
in patients with atrial fibrillation in engage af-timi
48[J]. Circulation,2019,139(6):760-771.
[23] MATHEWS L,ISHIGAMI J,DING N,et
al. Cardiac biomarkers and subsequent risk of
hospitalization with bleeding in the community:
atherosclerosis risk in communities study[J/OL]. J
Am Heart Assoc,2020,9(5):e013560[2021-05-
25]. https://doi.org/10.1161/jaha.119.013560.
[24] MARTI-FABREGAS J,MEDRANO-MARTORELL
S,MERINO E,et al. MRI predicts intracranial
hemorrhage in patients who receive long-term oral
anticoagulation[J/OL]. Neurology,2019,92(21):
e2432-e2443[2021-05-25]. https://doi.org/10.1212/
wnl.0000000000007532.
[25] SOO Y,ABRIGO J M,LEUNG K T,et al. Risk
of intracerebral haemorrhage in chinese patients
with atrial fibrillation on warfarin with cerebral
microbleeds:the ipaac-warfarin study[J]. J Neurol
Neurosurg Psychiatry,2019,90(4):428-435.
[26] WILSON D,AMBLER G,SHAKESHAFT C,et al.
Cerebral microbleeds and intracranial haemorrhage
risk in patients anticoagulated for atrial fibrillation
after acute ischaemic stroke or transient ischaemic
attack(CROMIS-2):a multicentre observational
cohort study[J]. Lancet Neurol,2018,17(6):539-
547.
[27] BADI M K,VILANILAM G K,GUPTA V,et al.
Pharmacotherapy for patients with atrial fibrillation
and cerebral microbleeds[J]. J Stroke Cerebrovas Dis,
2019,28(8):2159-2167.
[28] STANTON R J,ECKMAN M H,WOO D,et
al. Ischemic stroke and bleeding clinical benefit
of anticoagulation in atrial fibrillation after
intracerebral hemorrhage[J]. Stroke,2020,51(3):
808-814.
[29] DU H W,WILSON D,AMBLER G,et al. Small
vessel disease and ischemic stroke risk during
anticoagulation for atrial fibrillation after cerebral
ischemia[J]. Stroke,2021,52(1):91-99.
[30] GOTO S,GOTO S,PIEPER K S,et al. New
artificial intelligence prediction model using serial
prothrombin time international normalized ratio
measurements in atrial fibrillation patients on
vitamin K antagonists:GARFIELD-AF[J]. Eur
Heart J Cardiovasc Pharmacother,2020,6(5):301-
308.
[31] DOMEK M,GUMPRECHT J,MAZUREK M,et al.
Should we judge stroke risk by static or dynamic risk
scores? A focus on the dynamic nature of stroke and
bleeding risks in patients with atrial fibrillation[J]. J
Cardiovasc Pharmacol,2019,74(6):491-498.
[32] BIFFI A,URDAY S,KUBISZEWSKI P,et
al. Combining imaging and genetics to predict
recurrence of anticoagulation-associated
intracerebral hemorrhage[J]. Stroke,2020,51(7):
2153-2160.
[33] POGGESI A,BARBATO C,GALMOZZI F,et
al. Role of biological markers for cerebral bleeding
risk stratification in patients with atrial fibrillation
on oral anticoagulants for primary or secondary
prevention of ischemic stroke(STRAT-AF study):
study design and methodology[J]. Medicina,2019,
55(10):626.
[34] KURAMATSU J B,GERNER S T,SCHELLINGER
P D,et al. Anticoagulant reversal,blood pressure
levels,and anticoagulant resumption in patients with
anticoagulation-related intracerebral hemorrhage[J].
JAMA,2015,313(8):824-836.
[35] CHAO T F,LIU C J,LIAO J N,et al. Use of oral
anticoagulants for stroke prevention in patients with
atrial fibrillation who have a history of intracranial
hemorrhage[J]. Circulation,2016,133(16):1540-
1547.
[36] NEWMAN T V,CHEN N M,HE M Q,et
al. Effectiveness and safety of restarting oral
anticoagulation in patients with atrial fibrillation
after an intracranial hemorrhage:analysis of
medicare part d claims data from 2010-2016[J]. Am J
Cardiovasc Drugs,2020,20(5):471-479.
[37] PROIETTI M,ROMITI G F,ROMANAZZI I,et
al. Restarting oral anticoagulant therapy after
major bleeding in atrial fibrillation:a systematic
review and meta-analysis[J/OL]. Int J Cardiol,2018,
261:84-91[2021-05-25]. https://doi.org/10.1016/
j.ijcard.2018.03.053.
[38] PURRUCKER J C,HAAS K,WOLF M,et al.
Haernorrhagic transformation after ischaemic stroke
in patients taking non-vitamin k antagonist oral
anticoagulants[J]. J Stroke,2017,19(1):67-76.
[39] KERNAN W N,OVBIAGELE B,BLACK H R,et
al. Guidelines for the prevention of stroke in patients
with stroke and transient ischemic attack:a guideline
for healthcare professionals from the American Heart
Association/American Stroke Association[J]. Stroke,
2014,45(7):2160-2236.
[40] 中华医学会神经病学分会,中华医学会神经病学分
会脑血管病学组. 中国缺血性脑卒中和短暂性脑缺
血发作二级预防指南2014[J]. 中华神经科杂志,2015,
48(4):258-273.
[41] SMYTHE M A,PARKER D,GARWOOD C L,
et al. Timing of initiation of oral anticoagulation
after acute ischemic stroke in patients with atrial
fibrillation[J]. Pharmacotherapy,2020,40(1):55-
71.
[42] ROSE D Z,MERIWETHER J N,FRADLEY M G,
et al. Protocol for arest:apixaban for early prevention
of recurrent embolic stroke and hemorrhagic
transformation-a randomized controlled trial of
early anticoagulation after acute ischemic stroke in
atrial fibrillation[J/OL]. Frontiers in Neurology,2019,
10:975[2021-05-25]. https://doi.org/10.3389/fneur.
2019.00975.