Introduction of Clinical Study Design in Cerebrovascular Disease

doi:10.3969/j.issn.1673-5765.2022.01.003

Abstract

Abstract: The appropriate study design based on clinical questions is the basis of ensuring correct study results in clinical studies of cerebrovascular disease (CVD). The common types of CVD clinical studies includes cross-sectional study, case-control study, cohort study, clinical registry study and clinical trial. This article introduced the design principles, application situation and precautions of these common clinical studies, taking some examples of CVD studies to illustrate them, to provide a reference for selecting the right type of clinical study.

Key words: Clinical study; Cross-sectional study; Case-control study; Cohort study; Clinical registry study; Clinical trial

摘要： 在脑血管病临床研究过程中，根据临床问题选择适宜的临床研究设计方法是保证得到正确研究结果的基础。本文就脑血管病常见的临床研究类型，如横断面研究、病例对照研究、队列研究、临床登记研究和临床试验，简要介绍其基本方法、适用研究问题和应用注意事项等内容，并辅以案例加以分析，以期为不同脑血管病临床研究设计方法的合理选择提供参考意见。

关键词: 临床研究; 横断面研究; 病例对照研究; 队列研究; 临床登记研究; 临床试验

ZHANG Runhua, PAN Yuesong, JIANG Yong, LIU Gaifen. Introduction of Clinical Study Design in Cerebrovascular Disease[J]. Chinese Journal of Stroke, 2022, 17(01): 26-30.

张润华, 潘岳松, 姜勇, 刘改芬. 脑血管病临床研究设计的方法简介和实例分析[J]. 中国卒中杂志, 2022, 17(01): 26-30.

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