Chinese Journal of Stroke ›› 2024, Vol. 19 ›› Issue (7): 848-853.DOI: 10.3969/j.issn.1673-5765.2024.07.017

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The Status and Significance of Platelet Function Tests in the Assessment of Hemostatic Function in Neurosurgery

GUO Shuaiwei1, ZHANG Ya’nan2, WANG Shuo1   

  1. 1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

    2 Department of Blood Transfusion, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

  • Received:2023-06-05 Online:2024-07-20 Published:2024-07-20
  • Contact: WANG Shuo, E-mail: captain9858@126.com

血小板功能检测在神经外科止血功能评估中的现状与意义

郭帅炜1,张亚南2,王硕1   

  1. 1 北京 100070 首都医科大学附属北京天坛医院神经外科学中心

    2 首都医科大学附属北京天坛医院输血科

  • 通讯作者: 王硕 captain9858@126.com
  • 基金资助:
    国家重点研发计划课题(2021YFC2501103

Abstract: With the aging of the population, the proportion of patients receiving long-term antiplatelet therapy among those undergoing surgical treatment is increasing. Potential platelet hypofunction caused by antiplatelet drugs can affect intraoperative hemostasis and increase the risks of massive intraoperative hemorrhage and postoperative bleeding complications. Therefore, a quick and accurate assessment of platelet function before surgery is of great significance in comprehensively evaluating a patient’s hemostatic function. Based on the summary of relevant literature and the current status of the application of platelet function tests in neurosurgery, this paper analyzed the advantages and disadvantages of the currently commonly used platelet function tests, and introduced relevant therapies to improve platelet function, with the aim of improving the understanding of platelet function among neurosurgeons. 

Key words: Platelet function test; Antiplatelet therapy; Hemostasis; Neurosurgery

摘要:

随着人口老龄化,长期接受抗血小板治疗的患者在神经外科手术治疗人群中的比例不断增加。抗血小板药物导致的潜在血小板功能低下会影响术中止血效果,并增加术中大出血和术后出血并发症风险。因此,如何在术前快速准确地评估血小板功能,对于全面评估患者止血功能具有重要意义。本文通过总结相关文献,结合血小板功能检测在神经外科的使用现状,分析目前常用血小板功能检测方法的优缺点,介绍改善血小板功能的相关疗法,以期提高神经外科医师对血小板功能的认识。

关键词: 血小板功能检测; 抗血小板治疗; 止血; 神经外科

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