Abstract: Objective To analyze the clinical features of posterior circulation ischemia resulted from vertebrobasilar artery dissection.Methods Seven patients of vertebrobasilar artery dissection identified by magnetic resonance angiography(MRA) or digital subtraction angiography(DSA) or biopsy were retrospective analyzed.Results All seven patients complained of posterior circulation ischemic symptoms. The diagnosis of dissection was made by MRA in one patient, biopsy in another patient, and DSA in other fve patients. One patient was dead after thrombolysis with urokinase, three patients received antiplatelet agents, and three patients received angioplasty and stenting followed by antiplatelet agents. Six patients didn’t have any ischemic event during 3-24 months follow-up.Conclusion Vertebrobasilar artery dissection as one cause of posterior circulation ischemia, its identification is important for prognosis. Antiplatelet agents and interventional therapy may be effective.

Key words: Vetebral artery; dissection; Posterior circulation ischemia; Interventional therapy

摘要： 目的 分析椎-基底动脉夹层所致后循环缺血的临床特点。方法 对7例经磁共振血管造影（MRA）或全脑数字减影血管造影（DSA）证实的椎-基底动脉夹层患者的临床资料进行分析。结果 7例患者均表现为后循环缺血症状。其中1例患者经MRA诊断为椎动脉夹层，1例患者为尸检后确诊为椎-基底动脉夹层，另5例患者经DSA诊断。1例患者进行尿激酶溶栓治疗，3例进行抗血小板聚集治疗，3例进行支架成形术合并抗血小板聚集治疗。除1例溶栓治疗的患者死亡外，其余6例患者随访3～24个月均未发生缺血性卒中。结论 椎-基底动脉夹层是引起后循环缺血的原因之一，正确识别椎-基底动脉夹层对于患者预后至关重要。抗血小板聚集治疗和血管内治疗可能为椎-基底动脉夹层的有效治疗方法。

关键词: 椎动脉; 夹层; 后循环缺血; 介入治疗