Abstract: Objective To evaluate the diagnostic efficacy of Helicobacter pylori(Hp) stool antigen test (ImmunoCard STAT HpSA) and serological test (helicobacter pylori rapid test with current infection marker, CIM Hp RT) for Hp current infection in patients with cerebrovascular infarction.Methods Stool and boold samples of 93 patients were taken. The patients were evaluated with ImmunoCard STAT HpSA and CIM Hp RT. HpSA was detected using a lateral flow chromatography technique based on monoclonal antibody and Serology was done elsewhere using CIM Hp RT. Theresult assessment was taken by masked fashion. Analysis was carried out by paired Chi-square test(Mc Nemar Test) and the consistency of two determinations was evaluated using Kappa statistics.Results The prevalence of Hp current infection in patients with cerebrovascular infarction of ImmunoCard STAT HpSA and CIM Hp RT was 47.3%(44/93) and 52.7%(49/93), respectively.The total coincidence rate was 75.3%(70/93). There was no significant difference between the twodeterminations(P =0.405). The Kappa value for consistency was 0.507(95%CI 0.333-0.681, P <0.01).Conclusion The two determinations are helpful tools in the detection of Hp current infection in patients with cerebrovascular infarction and show moderate consistency.

Key words: Helicobacter pylori; Stool antigen; Serology; Infection; Brain infarction

摘要： 目的 比较分析幽门螺杆菌粪便抗原（helicobacter pylori stool antigen，HpSA）免疫快检卡与快速血清幽门螺杆菌现症感染带检测法（helicobacter pylori rapid test with current infection marker，CIM Hp RT）对脑梗死患者幽门螺杆菌（helicobacter pylori）现症感染的诊断价值。方法 获取93例患者的粪便和血液标本，HpSA的检测采用免疫色谱层析法的单克隆抗体进行，CIM Hp RT应用免疫层析法，结果判定采用盲法进行；应用配对（McNemar检验）和一致性检验（Kappa值）评价HpSA免疫快检卡与CIM Hp RT诊断脑梗死患者Hp现症感染的检出率，并进行比较。结果 HpSA免疫快检卡诊断脑梗死患者Hp现症感染检出率为47.3%（44/93），CIM Hp RT诊断脑梗死患者Hp现症感染检出率为52.7%（49/93），总符合率为75.3%（70/93），McNemar检验二者差异无统计学意义（P =0.405）；一致性检验的Kappa值为0.507（95%CI 0.333～0.681，P <0.01）。结论 HpSA免疫快检卡与CIM Hp快速检测法对脑梗死患者Hp现症感染的诊断能提供重要信息，且存在较好的一致性。

关键词: 螺杆菌; 幽门; 粪便抗原; 血清学; 感染; 脑梗塞