1 Wildgruber M, Swirski FK, Zernecke A. Molecularimaging of inf lammation in atherosclerosis[J].Theranostics, 2013, 3:865-884.2 Hayden MR, Tyagi SC. Uric acid:A new look at anold risk marker for cardiovascular disease, metabolicsyndrome, and type 2 diabetes mellitus:The urateredox shuttle[J]. Nutr Metab (Lond), 2004, 1:10.3 Lee YM, Bae SG, Lee SH, et al. Persistent organicpollutants and hyperuricemia in the U.S. generalpopulation[J]. Atherosclerosis, 2013, 230:1-5.4 Patetsios P, Song M, Shutze WP, et al. Identificationof uric acid and xanthine oxidase in atheroscleroticplaque[J]. Am J Cardiol, 2001, 88:188-191, A6.5 中华医学会内分泌学会. 高尿酸血症和痛风治疗的中国专家共识[J]. 中华内分泌代谢杂志, 2013, 29:913-920.6 Kanellis J, Feig DI, Johnson RJ. Does asymptomatichyperuricaemia contribute to the development ofrenal and cardiovascular disease? An old controversyrenewed[J]. Nephrology (Carlton), 2004, 9:394-399.7 Hermus L, Lefrandt JD, Tio RA, et al. Carotid plaqueformation and serum biomarkers[J]. Atherosclerosis,2010, 213:21-29.8 Nakagawa T, Mazzali M, Kang DH, et al. Hyperuricemiacauses glomerular hypertrophy in the rat[J]. Am JNephrol, 2003, 23:2-7.9 Kang DH, Han L, Ouyang X, et al. Uric acid causesvascular smooth muscle cell proliferation by enteringcells via a functional urate transporter[J]. Am JNephrol, 2005, 25:425-433.10 Kang DH, Park SK, Lee IK, et al. Uric acid-induced C-reactive protein expression:implication on cellproliferation and nitric oxide production of humanvascular cells[J]. J Am Soc Nephrol, 2005, 16:3553-3562.11 Nishi K, Itabe H, Uno M, et al. Oxidized LDL incarotid plaques and plasma associates with plaqueinstability[J]. Arterioscler Thromb Vasc Biol, 2002,22:1649-1654.12 Mathiesen EB, Bonaa KH, Joakimsen O. Low levelsof high-density lipoprotein cholesterol are associatedwith echolucent carotid artery plaques:the tromsostudy[J]. Stroke, 2001, 32:1960-1965.13 Schlotte V, Sevanian A, Hochstein P, et al. Effectof uric acid and chemical analogues on oxidation ofhuman low density lipoprotein in vitro[J]. Free RadicBiol Med, 1998, 25:839-847.14 Yur'Eva EA, Sukhorukov VS, Murashov AN, et al.Biochemical indicators of atherogenic and protectiveactivity of xydiphone in experimental animals[J]. BullExp Biol Med, 2012, 153:459-462.15 Kanellis J, Watanabe S, Li JH, et al. Uric acidstimulates monocyte chemoattractant protein-1production in vascular smooth muscle cells viamitogen-activated protein kinase and cyclooxygenase-2[J]. 2003, 41:1287-1293.16 Netea MG, Kullberg BJ, Blok WL, et al. The role ofhyperuricemia in the increased cytokine productionafter lipopolysaccharide challenge in neutrophnicmice[J]. Blood, 1997, 89:577-582.17 Ehara S, Kobayashi Y, Yoshiyama M, et al. Spottycalcification typifies the culprit plaque in patientswith acute myocardial infarction:an intravascularultrasound study[J]. Circulation, 2004, 110:3424-3429.18 Vengreny uk Y, Carlier S, Xanthos S, et al. Ahypothesis for vulnerable plaque rupture due to stressinduceddebonding around cellular microcalcificationsin thin fibrous caps[J]. Proc Natl Acad Sci U S A,2006, 103:14678-14683.19 Bost rom K, Wat son KE, Hor n S, et al. Bonemor phogenet ic prot ei n expr e s sion i n humanatherosclerotic lesions[J]. J Clin Invest, 1993, 91:1800-1809.20 O'Br ien ER, Ga r vi n MR, St ewa r t DK, e t a l.Osteopontin is synthesized by macrophage, smoothmuscle, and endothelial cells in pr ima r y andrestenotic human coronary atherosclerotic plaques[J].Arterioscler Thromb, 1994, 14:1648-1656.21 K h o s l a UM, Z h a r i k o v S , Fi n c h J L , e t a l .Hyperuricemia induces endothelial dysfunction[J].Kidney Int, 2005, 67:1739-1742.22 张雪光, 洪权, 侯凯, 等. 高尿酸通过miR-155下调eNOS表达而导致内皮细胞功能障碍[J]. 南方医科大学学报, 2013, 33:1141-1145.23 Ginsberg MH, Kozin F, O'Malley M, et al. Release ofplatelet constituents by monosodium urate crystals[J].J Clin Invest, 1977, 60:999-1007.24 Hink HU, Santanam N, Dikalov S, et al. Peroxidaseproperties of extracellular superoxide dismutase:roleof ur ic acid in modulating in vivo activity[J].Arterioscler Thromb Vasc Biol, 2002, 22:1402-1408.25 Neogi T, Ellison RC, Hunt S, et al. Serum uric acidis associated with carotid plaques:the National Heart,Lung, and Blood Institute Family Heart Study[J]. JRheumatol, 2009, 36:378-384.26 Ishizaka N, Ishizaka Y, Toda E, et al. Associationbetween serum uric acid, metabolic syndrome, andcarotid atherosclerosis in Japanese individuals[J].Arterioscler Thromb Vasc Biol, 2005, 25:1038-1044.27 李岩, 赵冬, 刘静, 等. 高尿酸血症与新发颈动脉粥样硬化斑块的关系[J]. 中华内科杂志, 2008, 47:906-909.28 Li Q, Yang Z, Lu B, et al. Serum uric acid level andits association with metabolic syndrome and carotidatherosclerosis in patients with type 2 diabetes[J].Cardiovasc Diabetol, 2011, 10:72.29 Fukui M, Tanaka M, Shiraishi E, et al. Serumuric acid is associated with microalbuminuria andsubclinical atherosclerosis in men with type 2 diabetesmellitus[J]. Metabolism, 2008, 57:625-629.30 Oikonen M, Wendelin-Saarenhovi M, LyytikainenLP, et al. Associations between serum uric acid andmarkers of subclinical atherosclerosis in young adults.The cardiovascular risk in Young Finns study[J].Atherosclerosis, 2012, 223:497-503.31 Cuspidi C, Valerio C, Sala C, et al. Lack of associationbetween serum uric acid and organ damage in anever-treated essential hypertensive population atlow prevalence of hyperuricemia[J]. Am J Hypertens,2007, 20:678-685.32 Jalal DI, Jablonski KL, McFann K, et al. Vascularendothelial function is not related to serum uric acidin healthy adults[J]. Am J Hypertens, 2012, 25:407-413. |