Research Progress of Circulating Leukocyte Telomere Length and Cardiovascular or Cerebrovascular Disease

Abstract

Abstract:

Accumulating studies have showed the association between telomere length and aging or diseases. Studies have showed that telomere length was associated with atherosclerosis. During the studies on cardiovascular and cerebrovascular diseases, the positive relationship between peripheral blood leukocyte telomere shortening and the risk of cardiovascular diseases was found, but the relationship between telomere length and cerebrovascular diseases was controversial. In this paper, the relationship between circulating leukocyte telomere length and cardiovascular or cerebrovascular diseases was reviewed.

Key words: Telomere length; Atherosclerosis; Stroke

摘要：

目前的研究显示端粒的长度与人类的衰老、疾病密切相关。研究显示端粒的长度与动脉粥样硬化相关。在心脑血管疾病的研究中发现外周血白细胞端粒缩短与心血管疾病风险正相关，但与脑血管疾病的关系尚有争议。本文就外周血白细胞端粒长度与心脑血管疾病之间的关系进行综述。

关键词: 端粒长度; 动脉粥样硬化; 卒中

LI Jing, ZHANG Mei, ZHANG Wei-Li. Research Progress of Circulating Leukocyte Telomere Length and Cardiovascular or Cerebrovascular Disease[J]. Chinese Journal of Stroke, 2016, 11(01): 82-86.

李静，张梅，张伟丽. 外周血白细胞端粒长度与心脑血管疾病风险的研究进展[J]. 中国卒中杂志, 2016, 11(01): 82-86.

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