Abstract:

Objective To investigate the diagnosis and treatment of post-stroke depression (PSD) in women,and to analysis PSD on old stroke women combination with diabetes mellitus (DM), coronary heartdisease (CHD) or high blood pressure (HBP).Methods From Oct 2009 to Oct 2010, 222 stroke inpatients were involved. To record the diagnosisof PSD and the treatment history, and to analysis the incidence of PSD on patients combined withDM, CHD and HBP.Results 1. Among the 222 stroke patients, 72 were diagnosed as PSD, and 40 of them were givenantidepressant. 2. The incidence of stroke patients combine with DM, CHD and HBP were 55.8%,47.4% and 39.7% respectively. The incidence of PSD on patients combined with DM and CHDwere higher than all patients.Conclusion Seventy-two of the 222 women (32.4%) had PSD. And there were significantdifferences between the stroke women with DM, CHD and all patients.

Key words: Depression; post-stroke; Diabetes mellitus; Coronary disease; Hypertension

摘要： 目的 调查女性缺血性卒中后抑郁（post-stroke depression，PSD）诊断及治疗情况，并分析女性缺血性卒中合并糖尿病、冠状动脉粥样硬化性心脏病及高血压后抑郁发生情况。方法 回顾性收集我院神经内科及老年科2009年10月至2010年10月期间住院>50岁的女性缺血性卒中患者资料，统计PSD发病率、诊断及药物治疗情况，并对合并糖尿病、冠状动脉粥样硬化性心脏病、高血压病患者PSD发病率进行统计分析。结果 ①结果显示222例女性缺血性卒中患者中有72例（32.4%）被诊断为PSD，其中40例给予抗抑郁药物治疗。②女性缺血性卒中合并糖尿病、冠状动脉粥样硬化性心脏病、高血压病组抑郁发病率分别为55.8%、47.4%、39.7%；合并糖尿病、冠状动脉粥样硬化性心脏病的缺血性卒中患者PSD发病率明显高于整体卒中患者（P分别为0.000和0.012）。结论 本次调查中50岁以上女性缺血性卒中患者PSD诊断率为32.4%；女性缺血性卒中患者合并糖尿病、冠状动脉粥样硬化性心脏病后抑郁发病率明显高于整体卒中患者。

关键词: 抑郁; 卒中后; 糖尿病; 冠状动脉疾病; 高血压