关键词: 缺血性卒中; 餐后高血糖; 下肢静脉; 血流动力学

Abstract:

Objective To investigate correlation between postprandial hyperglycemia and lower extremity venous blood flow mechanics in patients with ischemic stroke. Methods According to the results of 2-h plasma glucose in the oral glucose tolerance test (2hPG), 162 inpatients with anterior circulation light stroke were selected. They were divided into experimental group with postprandial hyperglycemia (n =90), and control group with normal blood glucose (n =72). After admission, color Doppler ultrasonography was used to examine the morphology and structure of the deep veins of the lower extremities in two groups, and the venous diameter and peak flow velocity of the lower extremities were measured. The biochemical indexes of the two groups were measured by automatic biochemical analyzer. Results There was no significant difference between the two groups in sex, age, smoking, alcohol consumption, hypertension, national institute of health stroke scale (NIHSS) score, body mass index (BMI), total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C) levels. The 2hPG level in experimental group was higher than normal group (P <0.05). The diameters of common iliac vein, iliac vein, femoral vein, popliteal vein in experimental group was greater than that of the control group (P <0.05). The peak velocity of common iliac vein, iliac vein, femoral vein, popliteal vein in experimental group was lower than control group (P <0.05), which had significant difference. Conclusion In patients with ischemic stroke accompanied by postprandial hyperglycemia, the blood flow velocity of the lower limb vein became slower and the diameter of the vein increased accordingly, which might increase the risk of venous thrombosis in the lower extremities and was unfavorable to the prognosis of the patients.

Key words: Ischemic stroke; Postprandial hyperglycemia; Lower extremity venous;Hemodynamics