关键词: 阿司匹林; 动脉粥样硬化; 环氧化酶; 脂氧素类; 一氧化氮

Abstract: Low-dose aspirin aspirin exerts anti-thrombotic action by acetylating and inactivating cyclooxygenase-1, preventing the production of thromboxane A2 in platelets, therefore low-dose aspirin is considered as a preventative of ischemic diseases such as myocardial and cerebral infarction. However, many studies have revealed that aspirin has other beneficial actions in addition to its antiplatelet activity. In this review, we discuss the involvement of inflammation in atherosclerosis and how Low-dose aspirin aspirin exerts its anti-inflammation action in atherosclerotic diseases.

Key words: Aspirin; Atherosclerosis; Cyclooxygenase; Lipoxin; Nitric oxide