关键词: 代谢综合征; 动脉粥样硬化; 脑梗死; 危险因素

Abstract: Objective To study the relationship between the metabolic syndrome (MS) with its components and atherothrombotic cerebral infarction(ATCI).Methods 508 ATCI patients (308 men and 200 women) who fulfilled the diagnostic criteria of the China Guideline for Cerebrovascular Disease Prevention and Treatment were enrolled. 233 control subjects (102 men and 131 women) without the clinical signs of cerebral infarction were selectedby detailed case history and physical examination and CT or MRI. The prevalence and risk of MS was observed in ATCI group and control. MS was defined by the modified criteria in Chinese.Results The prevalence of MS in ATCI groups was respectively 39.0% in men and 46.0% in women. The prevalence of MS was significantly high in ATCI groups compared with control subjects (P <0.01). The components level of MS had significant difference between ATCI groups and control subjects (P <0.05). The MS was associated with respectively 5.60 and 2.75 fold higherrisk of ATCI in men and women(P <0.01).Conclusion There was a close relationship between MS and ATCI. The MS was an important risk factor of ATCI.

Key words: 【Key Words】 Metabolic syndrome; Atherosclerosis; Cerebral infarction; Risk factor