›› 2012, Vol. 7 ›› Issue (05): 382-387.

• 论著 • 上一篇    下一篇

院内成人自发性脑出血患者短期存活影响因素分析

马爽,张硕,赵冬雪,郭阳   

  1. 沈阳中国医科大学附属盛京医院神经内科
  • 收稿日期:2011-09-20 修回日期:2011-08-20 出版日期:2012-05-20 发布日期:2012-05-20
  • 通讯作者: 郭阳

Short-Term Survival Influencing Factors Analysis in Adult Hospital Patients with Spontaneous Intracerebral Hemorrhage

MA Shuang, ZHANG Shuo, ZHAO Dong-Xue, et al   

  • Received:2011-09-20 Revised:2011-08-20 Online:2012-05-20 Published:2012-05-20
  • Contact: GUO Yang

摘要: 目的 探讨影响住院的成人自发性脑出血患者存活的因素,为临床判断预后提供简便可参考的方法。方法 运用回顾性研究的方法,收集成人自发性脑出血病例资料,将出院时结局评价为存活、死亡两组。以住院患者死亡作为观察终点。对年龄、出血破入脑室、脑水肿导致中线移位、入院时体温升高、在院期间血白细胞升高、在院期间肺部感染等19项临床资料进行详细记录,应用单因素、多因素Logistic回归分析等方法,探讨影响成人自发性脑出血患者短期存活的因素。结果 共收集成人自发性脑出血病例资料479例。①院内死亡率为11.48%。②单因素分析高龄(P=0.001)、缺血性卒中史(P=0.014)、出血破入脑室(P<0.001)、脑水肿导致中线移位(P<0.001)、入院时体温升高(P<0.001)、高血糖(P<0.001)、在院期间肺部感染(P<0.001)、出血量(P<0.001)、入院时心率(P<0.001)等因素与住院的自发性脑出血患者是否存活相关。③多因素Logistic回归分析,高龄(P=0.001)、缺血性卒中史(P=0.029)、高血糖(P=0.002)、出血量(P<0.001)、入院时心率(P<0.001)为影响住院的自发性脑出血患者短期存活的独立因素。结论 住院的成人自发性脑出血患者存在高龄、高血糖、缺血性卒中史、出血量大、入院时心率快等情况时,提示患者的短期预后不良,且以上因素为影响短期存活的独立因素。

关键词: 成人; 自发性脑出血; 存活

Abstract: Objective To explore the influencing factors of short-term survival in adults with spontaneous intracerebral hemorrhage(SICH) and to provide a simple and useful method of judging the prognosis in clinical.Methods Retrospective study was used in our study and the data of 479 consecutive hospitalized patients was collected, the ending of patients who leave hospital were divided into two groups(live group and dead group). The study would be stopped when the patients died. 19 kinds of clinical data were recorded intimately, and then we found and judged the influencing factors of short-term survival in adults with SICH by univariate analysis, and multiple factor logistic regression analysis.Results ①The mortality in the hospital is 11.48% in our study. ②Univariate analyses: age(P=0.001), ventricular extension(P<0.001), midline shifting(P<0.001), fever on admission(P<0.001), hyperglycaemia(P<0.001), pneumonia(P<0.001) et al were correlated with the short-term survival in adults with SICH. ③With the multiple factor logistic regression analysis we found age(P=0.001), hyperglycaemia(P=0.002), the amount of bleeding(P<0.001) et al were the independent predictors of SICH.Conclusion We found age, hyperglycaemia, the amount of bleeding, the history of ischemic stroke, and the heart rate on admission were the independent predictors of SICH.

Key words: Adults; Spontaneous intracerebral hemorrhage; Survival