›› 2012, Vol. 7 ›› Issue (01): 29-34.

• 论著 • 上一篇    下一篇

不同病因的皮质下小梗死的危险因素比较

李兰玉,李焰生   

  1. 上海交通大学医学院附属仁济医院神经科
  • 收稿日期:2011-06-22 修回日期:2011-05-22 出版日期:2012-01-20 发布日期:2012-01-20
  • 通讯作者: 李焰生

Comparison of Vascular Risk Factors in Patients with Small Subcortical Infarction Caused by Atherosclerosis or Small Artery Disease

LI Lan-Yu, LI Yan-Sheng.   

  • Received:2011-06-22 Revised:2011-05-22 Online:2012-01-20 Published:2012-01-20
  • Contact: LI Yan-Sheng

摘要: 【摘要】目的 观察皮质下小的脑梗死(small subcortical infarction,SSI)与颅内外大动脉病变的关系。比较动脉粥样硬化性与小动脉病变性SSI患者的危险因素的差异。方法 连续收集住院的118例急性SSI患者,依据循证的缺血性卒中病因分型诊断标准停止卒中研究-急性卒中治疗Org 10172试验(Stop Stroke Study Trial of Org 10172 in Acute Stroke TreatmentClassification System,SSS-TOAST)进行卒中分型,比较不同血管病因所导致的SSI的比例,分析不同病因患者的血管性危险因素的差异。结果 118例急性SSI患者中,动脉粥样硬化性者26例(22%)、小动脉病变者75例(64%),心源性、其他明确病因及病因不明确者17例(14%)。动脉粥样硬化病变者与小动脉病变者的主要血管性危险因素分布差异无统计学意义。结论 SSI患者的病因并非相同,以小动脉病变居多。动脉粥样硬化性和小动脉病变性SSI在血管危险因素分布之间差异无统计学意义。

关键词: 脑梗死; 动脉粥样硬化; 小动脉硬化; 危险因素

Abstract: Objective To analyze the association between small subcortical infarctions(SSIs) and extracranialor intracranial artery disease. To compare the vascular risk factors in SSI caused by atherosclerosisand small artery disease.Methods Serial hospitalized patients with acute SSI were enrolled. Patients were classified intodifferent groups according to the Stop Stroke Study Trial of Org 10172 in Acute Stroke TreatmentClassification System. The frequencies of SSI with different causes and their vascular risk factorswere collected and compared.Results Among total 118 patients with SSI, 26 were caused by atherosclerosis, 75 were caused bysmall-artery diseases, and 17 were caused by other causes. There were no significant differences ofrisk factors between the group of atherosclerosis and the group of small-artery diseases(P >0.05).Conclusion SSIs are caused by different etiologies but mainly small-artery diseases. There are nosignificant differences of vascular risk factors between SSI caused by atherosclerosis or small arterydiseases.

Key words: Brain infarction; Atherosclerosis; Arteriolosclerosis; Risk factors