1 Gorelick PB，Wong KS，Bae HJ，et al. Large artery

intracranial occlusive disease：a large worldwide

burden but a relatively neglected frontier[J]. Stroke，2008，39：2396-2399.

2 Deg na n AJ，Gal lagher G，Teng Z，et a l. MR

angiography and imaging for the evaluation of middle

cerebral artery atherosclerotic disease[J]. AJNR Am J

Neuroradiol，2012，33：1427-1435.

3 Tian L，Yue X，Xi G，et al. Multiple intracranial

arterial stenosis influences the long-term prognosis

of symptomatic middle cerebral artery occlusion[J].

BMC Neurol，2015，15：68.

4 McVerry F，Liebeskind DS，Muir KW. Systematic

review of methods for assessing leptomeningeal

collateral flow[J]. AJNR Am J Neuroradiol，2012，33：

576-582.

5 Calleja AI，Cor tijo E，García-Bermejo P，et al.

Collateral ci rculation on per fusion-computed

tomography-source images predicts the response

to stroke intravenous thrombolysis[J]. Eur J Neurol，

2013，20：795-802.

6 Kim Y，Sin DS，Park HY，et al. Relationship between

flow diversion on transcranial Doppler sonography

and leptomeningeal collateral circulation in patients

with middle cerebral artery occlusive disorder[J]. J

Neuroimaging，2009，19：23-26.

7 Hwang YH，Kang DH，Kim YW，et al. Impact of

time-to-reperfusion on outcome in patients with poor

collaterals[J]. AJNR Am J Neuroradiol，2015，36：

495-500.

8 Bodle JD，Feldmann E，Swartz RH，et al. Highresolution

magnetic resonance imaging：an emerging

tool for evaluating intracranial arterial disease[J].

Stroke，2013，44：287-292.

9 Cho ZH，Lee YB，Kang CK，et al. Microvascular

imaging of asymptomatic MCA steno-occlusive

patients using ultra-high-field 7T MRI[J]. J Neurol，

2013，260：144-150.

10 Yang WQ，Huang B，Liu XT，et al. Reproducibility

of high-resolution MRI for the middle cerebral artery

plaque at 3T[J]. Eur J Radiol，2014，83：e49-55.

11 Liu D，Li Y，Shi Z，et al. Presence of anterior

temporal artery associates with good outcome in

acute atherosclerotic M1-middle cerebral artery

occlusion[J]. Neuroradiology，2014，56：1023-1030.

12 Lima FO，Furie KL，Silva GS，et al. Prognosis of

untreated strokes due to anterior circulation proximal

intracranial arterial occlusions detected by use of

computed tomography angiography[J]. JAMA Neurol，

2014，71：151-157.

13 Huang X，Liu W，Zhu W，et al. Distal hyperintense

vessels on FLAIR：a prognostic indicator of acute

ischemic stroke[J]. Eur Neurol，2012，68：214-220.

14 Haussen DC，Koch S，Saraf-Lavi E，et al. FLAIR

distal hyperintense vessels as a marker of perfusiondiffusion

mismatch in acute stroke[J]. J Neuroimaging，

2013，23：397-400.

15 Xu WH，Li ML，Niu JW，et al. Deep tiny flow voids

along middle cerebral artery atherosclerotic occlusions：

a high-resolution MR imaging study[J]. J Neurol Sci，

2014，339：130-133.

16 Xu WH，Li ML，Niu JW，et al. Luminal thrombosis

in middle cerebral artery occlusions：a high-resolution

MRI study[J]. Ann Transl Med，2014，2：75.

17 Xu WH，Li ML，Gao S，et al. In vivo high-resolution

MR imaging of symptomatic and asymptomatic

middle cerebral artery atherosclerotic stenosis[J].

Atherosclerosis，2010，212：507-511.

18 Xu WH，Li ML，Gao S，et al. Middle cerebral artery

intraplaque hemorrhage：prevalence and clinical

relevance[J]. Ann Neurol，2012，71：195-198.

19 Huttner HB，Schwab S. Malignant middle cerebral

artery infarction：clinical characteristics，treatment

strategies，and future perspectives[J]. Lancet Neurol，

2009，8：949-958.

20 Liu J，Wang Y，Akamatsu Y，et al. Vascular remodeling

after ischemic stroke：mechanisms and therapeutic

potentials[J]. Prog Neurobiol，2014，115：138-156.

21 Wa n g YQ，Gu o X，Qi u MH，e t a l . VEGF

overexpression enhances striatal neurogenesis in brain

of adult rat after a transient middle cerebral artery

occlusion[J]. J Neurosci Res，2007，85：73-82.

22 Gr el l AS，Thigar ajah R，Edvinsson L，e t a l.

Regulatory mechanism of endothelin receptor B in

the cerebral arteries after focal cerebral ischemia[J].

PLoS One，2014，9：e113624.

23 Liebeskind DS. Collateral perfusion：time for novel

paradigms in cerebral ischemia[J]. Int J Stroke，2012，

7：309-310.