关键词: 脑桥梗死; 基底动脉; 穿支; 动脉粥样硬化; 临床特征

Abstract:

Objective To compare the clinical features and the pathogenesis of different types of pontine infarction. Methods A total of 75 patients with pontine infarction were divided into basilar artery stenosis group (n =9) and basilar artery non-stenosis group (n =66). Among which , basilar artery nonstenosis group were divided into perforating disease group (n =33) and small artery disease group (n =33). The clinical features and imaging changes of each group were compared. Results The incidence of diabetes mellitus, coronary heart disease, intracranial artery atherosclerotic stenosis, admission National Institutes of Health Stroke Scale (NIHSS) score, discharged NIHSS score and modified Rankin Scale (mRS) score ≥3 were significantly higher in BA stenosis group (P <0.05). The incidence of fasting and 2 h postprandial plasma glucose, glycosylated hemoglobin, admission systolic pressure, the infarct size, admission NIHSS and discharged NIHSS score, and mRS score were significantly higher in basilar branch disease group than in small vascular disease group (P <0.05). Conclusion There are different causes and pathogenesis of pontine infarction. The lesions of paramedian pontine infarction with basilar artery stenosis are characterized by atherosclerosis, large lesion, severe symptoms, easy progression and poor prognosis.

Key words: Pontine infarction; Basilar artery; Perforating branch; Atherosclerosis; Clinical features