Chinese Journal of Stroke ›› 2017, Vol. 12 ›› Issue (08): 720-724.DOI: 10.3969/j.issn.1673-5765.2017.08.013

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The Precision Diagnosis and Treatment of Intracranial Arterial Lesions with High-resolution Magnetic Resonance Imaging

  

  • Received:2017-05-10 Online:2017-08-20 Published:2017-08-20

高分辨率磁共振成像对颅内动脉病变的精准化诊疗

徐曼曼,徐运   

  1. 210008 南京大学医学院附属鼓楼医院神经内科
  • 通讯作者: 徐运 xuyun20042001@aliyun.com
  • 基金资助:

    国家重点研发计划重点专项(2016YFC1300500-504)
    江苏省科技厅医学重点项目(BE2016610)
    江苏省医学重点学科(ZDXKA2016020)

Abstract:

Vessel wall imaging can depict the morphologies of atherosclerotic plaques, arterial walls, and surrounding structures in the intracranial and cervical carotid arteries beyond the simple luminal changes that can be observed with traditional luminal evaluation. There are around 6-7 million cases of stroke every year in china, among which, 46.6% of acute ischemic stroke are caused by cerebrovascular disease. Its pathogen is complicated (intracranial artery atherosclerosis, dissection, Moyamoya disease, etc.); intracranial arterial diameter is small; and the position is relatively deep. It is difficult to find small lesions of vessels and recognize the characteristic because of traditional imaging methods with limited spatial resolution. Correct identification of intracranial arterial disease is essential for early diagnosis, prevention and treatment. However, high-resolution magnetic resonance imaging (HR-MRI) has a dual imaging of the wall and lumen, which is an emerging important and popular technique and can be directly used in the evaluation of intracranial vasculopathies. This article aims to clarify the precision diagnosis and treatment of intracranial arterial lesions through HR-MRI.

Key words: High-resolution magnetic resonance; Intracranial atherosclerosis; Moyamoya disease; Dissection; Precision diagnosis and treatment

摘要:

血管壁成像(vessel wall imaging,VWI)可以显示除传统管腔影像检测到的简单管腔病变 之外的变化,如动脉粥样硬化性斑块形态、动脉管壁和颅内及颈部动脉周围结构组织。我国现有卒 中患者600万~700万人/年,46.6%的急性缺血性卒中由颅内血管病变所致。颅内动脉病变病因多(颅 内动脉粥样硬化、烟雾病、夹层等),并且颅内动脉血管管径小,位置较深,传统影像学检查方法因 其空间分辨率有限,难以发现血管微小病变,不能明确病变性质。正确识别颅内动脉病变原因对其 早期诊断、预防和治疗至关重要。而高分辨率磁共振成像(high-resolution magnetic resonance imaging, HR-MRI)具有管壁和管腔双重成像作用,是直接评估颅内动脉疾病的重要并最受欢迎的新兴成像技 术。本文旨在通过HR-MRI对颅内动脉病变的精准化诊疗做一综述。

关键词: 高分辨率磁共振; 颅内动脉粥样硬化; 烟雾病; 夹层; 精准化诊疗